![5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carbo…](https://static.cymitquimica.com/cas-image/thumb-webp/487339-orm-15341.webp)
CAS 1297537-33-7
:5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carboxamide
Description:
5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carboxamide, with CAS number 1297537-33-7, is a synthetic organic compound characterized by its complex pyrazole structure, which includes multiple functional groups such as an acetyl group and a carboxamide. This compound features a chiral center, contributing to its stereochemistry, and exhibits potential biological activity due to the presence of the pyrazole moiety, which is often associated with pharmacological properties. The chlorinated phenyl group enhances its lipophilicity, potentially influencing its interaction with biological targets. The compound's solubility, stability, and reactivity can vary based on environmental conditions and the presence of other substances. Its synthesis typically involves multi-step organic reactions, and it may be of interest in medicinal chemistry for its potential therapeutic applications. As with many pyrazole derivatives, it may exhibit anti-inflammatory, analgesic, or other bioactive properties, warranting further investigation in drug development contexts.
Formula:C19H17ClN6O2
InChI:InChI=1S/C19H17ClN6O2/c1-11(22-19(28)18-8-17(12(2)27)23-24-18)10-26-6-5-16(25-26)13-3-4-14(9-21)15(20)7-13/h3-8,11H,10H2,1-2H3,(H,22,28)(H,23,24)/t11-/m0/s1
InChI key:InChIKey=GMBPVBVTPBWIKC-NSHDSACASA-N
SMILES:C([C@@H](NC(=O)C=1C=C(C(C)=O)NN1)C)N2N=C(C=C2)C3=CC(Cl)=C(C#N)C=C3
Synonyms:- 1H-Pyrazole-3-carboxamide, 5-acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-
- 5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carboxamide
- (S)-5-Acetyl-N-[1-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]propan-2-yl]-1H-pyrazole-3-carboxamide
- ORM 15341
- ORM-15341(Ketodarolutamide)
- (S)-3-acetyl-N-(1-(3-(3-chloro-4-cyano-phenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-5-carboxamide
- Ketodarolutamide
Filter by
Purity percentage
0
100
|
0
|
50
|
90
|
95
|
100
Found 8 products.
- Lower prices
- Higher prices
- Lower purities
- Higher purities
- Faster estimated delivery
5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carboxamide
CAS:Formula:C19H17ClN6O2Purity:99%Color and Shape:SolidMolecular weight:396.8303ORM-15341
CAS:ORM-15341 is a potent and full antagonist for human AR (hAR)( with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells)Formula:C19H17ClN6O2Purity:98.01%Color and Shape:SolidMolecular weight:396.83ORM-15341
CAS:Applications ORM-15341 is a metabolite of Darolutamide. Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models.
References Sugawara, T., et al.: Int. J. Cancer, 145, 1382 (2019); Yu, J., et al.: Eur. J. Med. Chem., 182, 111608 (2019)Formula:C19H17ClN6O2Color and Shape:NeatMolecular weight:396.83ORM-15341
CAS:Please enquire for more information about ORM-15341 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C19H17ClN6O2Purity:Min. 95%Molecular weight:396.83 g/mol
![5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carbo…](https://static.cymitquimica.com/products/IN/thumb/DA009CJH.jpg)
