CymitQuimica logo

CAS 129816-30-4

:

5'-O-(tert-Butyldimethylsilyl)-5-fluoro-2'-deoxyuridine

Description:
5'-O-(tert-Butyldimethylsilyl)-5-fluoro-2'-deoxyuridine is a modified nucleoside analog that features a fluorine atom at the 5-position of the uracil base, which enhances its potential for antiviral and anticancer applications. The tert-butyldimethylsilyl (TBDMS) group at the 5'-hydroxyl position serves as a protective group, facilitating further chemical modifications and improving the compound's stability during synthesis. This compound is typically used in nucleic acid research and drug development due to its ability to mimic natural nucleosides while providing unique properties. Its structural modifications can influence its solubility, permeability, and biological activity, making it a valuable tool in the study of nucleic acid interactions and the development of therapeutic agents. The presence of the fluorine atom can also enhance the binding affinity to specific targets, potentially leading to improved efficacy in therapeutic applications. Overall, this compound exemplifies the strategic modifications made to nucleosides to enhance their functionality in biochemical research and pharmaceutical development.
Formula:C15H25FN2O5Si
Synonyms:
  • 5'-O-TBDMSoxy-5-Fluoro-2'-deoxyuridine
  • 5'-O-TBDMS-5-Fluoro-2'-deoxyuridine
  • 5'-O-TBDMS-5-F-dU
  • 5'-O-(tert-Butyldimethylsilyl)-5-fluoro-2'-deoxyuridine
  • Uridine, 2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-fluoro- (9CI)
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.