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CAS 129828-71-3

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L-myo-inositol 1,4,5-tris-*phosphate potassium

Description:
L-myo-inositol 1,4,5-trisphosphate potassium, commonly referred to as Ins(1,4,5)P3 potassium salt, is a phosphorylated inositol derivative that plays a crucial role in cellular signaling pathways. It is primarily involved in the regulation of intracellular calcium levels and is a key second messenger in various biological processes, including cell proliferation, differentiation, and apoptosis. The compound is soluble in water, which facilitates its role in cellular signaling. Its structure features a myo-inositol backbone with three phosphate groups attached at the 1, 4, and 5 positions, contributing to its high polarity and reactivity. The potassium salt form enhances its stability and solubility in physiological conditions. L-myo-inositol 1,4,5-trisphosphate is synthesized in response to various extracellular signals and is rapidly metabolized by specific phosphatases, highlighting its transient nature in signaling cascades. Due to its significant biological functions, it is of interest in research related to neurobiology, endocrinology, and cancer biology.
Formula:C6H9K6O15P3
InChI:InChI=1/C6H15O15P3.6K/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12;;;;;;/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18);;;;;;/q;6*+1/p-6/t1-,2+,3+,4-,5-,6-;;;;;;/m0....../s1
SMILES:C1(C(C(C(C(C1OP(=O)(O)O)O)OP(=O)(O)O)OP(=O)(O)O)O)O.K.K.K.K.K.K
Synonyms:
  • L-myo-Inositol 1,4,5-Trisphosphate, Hexapotassium Salt
  • hexapotassium (1S,2S,3R,4S,5S,6R)-3,5,6-trihydroxycyclohexane-1,2,4-triyl tris(phosphate)
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