CAS 130-26-7
:Clioquinol
Description:
Clioquinol, with the CAS number 130-26-7, is an organic compound that belongs to the class of quinoline derivatives. It is primarily recognized for its use as an antimicrobial agent and has been employed in the treatment of various gastrointestinal infections. Clioquinol exhibits a yellow crystalline appearance and is soluble in organic solvents, such as ethanol and chloroform, but has limited solubility in water. The compound possesses both antibacterial and antifungal properties, making it effective against a range of pathogens. However, its use has been associated with potential neurotoxicity, leading to restrictions in its clinical applications. Clioquinol acts by chelating metal ions, which can disrupt microbial metabolism. Its chemical structure includes a quinoline ring and a hydroxyl group, contributing to its biological activity. Due to its historical significance and the controversies surrounding its safety, clioquinol remains a subject of research, particularly in the context of neurodegenerative diseases and its potential therapeutic roles.
Formula:C9H5ClINO
InChI:InChI=1/C10H6ClIO/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,13H
InChI key:InChIKey=QCDFBFJGMNKBDO-UHFFFAOYSA-N
SMILES:OC=1C2=C(C(Cl)=CC1I)C=CC=N2
Synonyms:- 5-Chloro-7-iodo-8-hydroxyquinoline
- 5-Chloro-7-iodo-8-oxyquinoline
- 5-Chloro-7-iodo-8-quinolinol
- 5-Chloro-7-iodoquinolin-8-ol
- 7-Iodo-5-chloro-8-hydroxyquinoline
- 7-Iodo-5-chloroxine
- 8-Hydroxy-7-iodo-5-chloroquinoline
- 8-Quinolinol, 5-chloro-7-iodo-
- Alchloquin
- Amebil
- Amoenol
- Bactol
- Barquinol
- Budoform
- Chinoform
- Chloroiodoquin
- Chloroiodoquine
- Chlorojodochin
- Cifoform
- Clioquinol
- Cliquinol
- Cort-Quin
- Dioquinol
- Dizenterol
- Eczecidin
- Emaform
- Entero-Vioform
- Enteroquinol
- Enteroseptol
- Enterozol
- Entrokin
- Hi-Eneterol
- Hi-Enterol
- Iodenterol
- Iodochlorhydroxyquin
- Iodochlorhydroxyquinol
- Iodochlorohydroxyquin
- Iodochlorohydroxyquinoline
- Iodochloroquine
- Iodochloroxine
- Iodochloroxyquinoline
- Iodoenterol
- Iodoxyquinoline
- Lekosept
- NSC 3531
- NSC 74938
- Nioform
- Quin-O-Creme
- Quinambicide
- Quinidochlor
- Quiniodochlor
- Quinoform
- Quinoform (antiseptic)
- Rheaform
- Rheaform Boluses
- Rometin
- Vioform
- Vioformio
- 5-Chlor-7-jod-8-hydroxy-chinolin
- AKOS B020410
- ala-quin
- 5-chloro-7-iodo-8-quinolino
- alchoquin
- chloroiodeoquim
- N-IODO-5-CHLORO-8-HYDROXYQUINOLINE
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 17 products.
5-Chloro-8-hydroxy-7-iodoquinoline
CAS:Formula:C9H5ClINOPurity:>97.0%(T)Color and Shape:Light yellow to Brown to Dark green powder to crystalMolecular weight:305.50CLIOQUINOL CRS
CAS:CLIOQUINOL CRSFormula:C9H5ClINOColor and Shape:White. Whitish. Yellow. Dark. Powder.Molecular weight:305.4996Clioquinol
CAS:ClioquinolFormula:C9H5ClINOPurity:99.9%Color and Shape:Off-WhiteMolecular weight:304.91044Clioquinol
CAS:Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fusedFormula:C9H5ClINOColor and Shape:PowderMolecular weight:304.910445-Chloro-7-Iodoquinolin-8-ol
CAS:Formula:C9H5ClINOPurity:97%Color and Shape:SolidMolecular weight:305.4996Clioquinol
CAS:<p>Clioquinol: oral, lipophilic copper-binder; halogenated quinoline with antifungal, antiparasitic, and possible antitumor uses.</p>Formula:C9H5ClINOPurity:97.02%Color and Shape:Brownish-Yellow Bulky Powder Decomposes At 178-179°C Used As A Topical Anti-InfectiveMolecular weight:305.5Clioquinol
CAS:Formula:C9H5ClINOPurity:≥ 95.0%Color and Shape:White to light-yellow, yellow or brown powder or crystalsMolecular weight:305.495-Chloro-8-hydroxy-7-iodoquinoline
CAS:5-Chloro-8-hydroxy-7-iodoquinolineFormula:C9H5ClINOPurity:≥95%Color and Shape: cream powderMolecular weight:305.50g/molClioquinol
CAS:Controlled Product<p>Applications Clioquinol is used as an antiparasitic compound, known to induce apoptosis in leukemia and myeloma cells.<br>References Cao, B. et al.: J. Biol. Chem., 288, 34181 (2013); Chen, Z. et al.: Eur J. Med. Chem., 68, 454 (2013);<br></p>Formula:C9H5ClINOColor and Shape:NeatMolecular weight:305.505-Chloro-7-iodo-8-hydroxyquinoline
CAS:<p>5-Chloro-7-iodo-8-hydroxyquinoline is a metal chelate that has been shown to have pharmacological effects in experimental animals. It has antioxidative properties and can protect against oxidative injury. 5-Chloro-7-iodo-8-hydroxyquinoline was found to be toxic in various animal models, including the neuronal death and mitochondrial membrane potential. This toxicity may be due to its ability to inhibit the activity of DNA polymerase and protein synthesis. The compound also showed significant cytotoxicity at low concentrations, but had no significant cytotoxicity at higher concentrations. 5-Chloro-7-iodo-8-hydroxyquinoline is similar in structure to clioquinol, which has been shown to have neurotoxic effects in humans.</p>Formula:C9H5ClINOPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:305.5 g/molClioquinol - Bio-X ™
CAS:<p>Clioquinol is an antifungal drug and antiprotozoal drug that has been shown to inhibit the activity of protein kinase-3 and to promote apoptosis. This compound has also been found to improve iron homeostasis, which may be due to its ability to counteract the effects of oxidative stress on the mitochondria. Additionally, it has been shown to have anti-fungal properties against opportunistic fungal pathogens such as Candida albicans. Clioquinol is extracted from a plant called "Clioquinia rosea" and is produced by a chemical reaction with 2-chloroethanol.</p>Formula:C9H5ClINOPurity:Min. 95%Color and Shape:PowderMolecular weight:305.5 g/mol5-Chloro-7-Iodo-8-Quinolinol (Clioquinol, Iodochlorohydroxyquinoline) ExiPlus, Multi-Compendial, 97-103%
CAS:Formula:C9H5ClINOPurity:97.0-103.0%Color and Shape:White to Light Yellow to Light Beige, Powder or Crystals, ClearMolecular weight:305.5
