CAS 130-61-0
:Thioridazine hydrochloride
Description:
Thioridazine hydrochloride is an antipsychotic medication primarily used to treat schizophrenia and other psychotic disorders. It belongs to the phenothiazine class of compounds, which are characterized by a three-ring structure that includes a sulfur atom. Thioridazine acts primarily as a dopamine antagonist, blocking dopamine receptors in the brain, which helps to alleviate symptoms of psychosis. The hydrochloride salt form enhances its solubility and stability. In terms of physical characteristics, thioridazine hydrochloride is typically a white to off-white crystalline powder. It is soluble in water and alcohol, with a relatively low melting point. The compound may exhibit side effects, including sedation, anticholinergic effects, and potential cardiovascular issues, necessitating careful monitoring during treatment. Additionally, thioridazine has been associated with a risk of QT prolongation, which can lead to serious heart rhythm disturbances. As with any medication, it is essential to use thioridazine hydrochloride under the guidance of a healthcare professional, considering its therapeutic benefits and potential risks.
Formula:C21H26N2S2·ClH
InChI:InChI=1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H
InChI key:InChIKey=NZFNXWQNBYZDAQ-UHFFFAOYSA-N
SMILES:C(CC1N(C)CCCC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(SC)C3.Cl
Synonyms:- 10-(2-(1-Methyl-2-Piperidinyl)Ethyl)-2-(Methylthio)-10H-Phenothiazinmono
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
- 10-[2-(1-Methyl-2-Piperidyl)-Ethyl]-2-[Methylthiol]-Phenothiazine Hydrochloride
- 10-[2-(1-Methyl-2-Piperidyl)Ethyl]-2-(Methylthio)-10H-Phenothiazine Hydrochloride
- 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
- 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
- 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride (1:1)
- 10-[3-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine hydrochloride
- 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
- 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, hydrochloride (1:1)
- 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride (9CI)
- 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
- 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
- Aldazine
- Labotest-Bb Lt00451961
- Mallorol
- Mellaril
- Mellaril hydrochloride
- Melleretten
- Melleril
- NSC 186060
- Novoridazine
- Orsanil
- Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, hydrochloride
- Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, monohydrochloride
- Ridazin
- Stalleril
- THIORIDAZINEHYDROCHLORIDE,USP
- ThioridazinHCl
- Thioridazine Hcl
- Thioridazinhydrochlorid
- Thioril
- Thiozine
- mellarilhydrochloride
- melleril(tablet)
- usafsz-3
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
- 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
- mellarilhydrochloride
- melleril(tablet)
- usafsz-3
- ThioridazinHCl
- Thioridazinhydrochlorid
- 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
- 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
- Orsanil
- Ridazin
- Stalleril
- 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
- THIORIDAZINEHYDROCHLORIDE,USP
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Found 15 products.
Thioridazine Hydrochloride
CAS:Formula:C21H26N2S2·HClPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:407.03THIORIDAZINE HYDROCHLORIDE CRS
CAS:THIORIDAZINE HYDROCHLORIDE CRSFormula:C21H27ClN2S2Color and Shape:PowderMolecular weight:407.0355Thioridazine Hydrochloride
CAS:Antidepressants, tranquilizers and other pschotherapeutic agentsFormula:C21H26N2S2·ClHColor and Shape:PowderMolecular weight:406.13042Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formula:C21H27ClN2S2Purity:99.55% - 99.957%Color and Shape:White To Off-White SolidMolecular weight:407.04Thioridazine HCl
CAS:Formula:C21H26N2S2·HClColor and Shape:White To Off-White SolidMolecular weight:370.58 36.46Thioridazine hydrochloride
CAS:Formula:C21H26N2S2·HClPurity:≥ 98.0%Color and Shape:White to off-white powder or crystalsMolecular weight:407.03Thioridazine Hydrochloride
CAS:Controlled ProductFormula:C21H26N2S2·ClHColor and Shape:NeatMolecular weight:407.04Thioridazine hydrochloride
CAS:Controlled ProductFormula:C21H26N2S2·ClHColor and Shape:NeatMolecular weight:407.0410-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
CAS:10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochlorideFormula:C21H26N2S2·ClHPurity:98%Color and Shape: white solidMolecular weight:407.04g/molThioridazine Hydrochloride
CAS:Controlled Product<p>Applications Thioridazine HCl is a dopamine receptor blocker and antipsychotic. It is the parent compound of sulforidazine and mesoridazine. This compound has been reported to bind strongly to dopamine receptors on cancer stem cells and cause differentiation leaving normal cells alone (see Can. Chem. News 12 July/August 2012).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),<br></p>Formula:C21H26N2S2·ClHColor and Shape:Light YellowMolecular weight:407.0410-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride
CAS:Controlled Product<p>The drug, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride (CGP 46660), is a competitive antagonist at the human histamine H3 receptor. It has been shown to bind to the histamine H3 receptor in the range of 0.001 to 1 μM and is selective for this receptor over other receptors. CGP 46660 is an optical sensor that can be used in titration calorimetry experiments to measure changes in heat production when it binds to histamine H3 receptors. The drug also has been shown to inhibit guanine nucleotide-binding protein (G protein) signaling pathways and brain functions such as memory formation, learning, and attention span. These effects were demonstrated in humans by measuring EEG activity. The optimum concentration of CGP 46660 for these effects was found to be between 0.01 and 10 μM.</p>Formula:C21H27ClN2S2Purity:Min. 95%Color and Shape:PowderMolecular weight:407.04 g/mol
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