CAS 130-61-0: Thioridazine hydrochloride
Description:Thioridazine hydrochloride is an antipsychotic medication primarily used to treat schizophrenia and other psychotic disorders. It belongs to the phenothiazine class of compounds, which are characterized by a three-ring structure that includes a sulfur atom. Thioridazine acts primarily as a dopamine antagonist, blocking dopamine receptors in the brain, which helps to alleviate symptoms of psychosis. The hydrochloride salt form enhances its solubility and stability. In terms of physical characteristics, thioridazine hydrochloride is typically a white to off-white crystalline powder. It is soluble in water and alcohol, with a relatively low melting point. The compound may exhibit side effects, including sedation, anticholinergic effects, and potential cardiovascular issues, necessitating careful monitoring during treatment. Additionally, thioridazine has been associated with a risk of QT prolongation, which can lead to serious heart rhythm disturbances. As with any medication, it is essential to use thioridazine hydrochloride under the guidance of a healthcare professional, considering its therapeutic benefits and potential risks.
Formula:C21H26N2S2·ClH
InChI:InChI=1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H
InChI key:InChIKey=NZFNXWQNBYZDAQ-UHFFFAOYSA-N
SMILES:Cl.S1C=2C=CC=CC2N(C3=CC(SC)=CC=C13)CCC4N(C)CCCC4
- Synonyms:
- 10-(2-(1-Methyl-2-Piperidinyl)Ethyl)-2-(Methylthio)-10H-Phenothiazinmono
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
- 10-[2-(1-Methyl-2-Piperidyl)-Ethyl]-2-[Methylthiol]-Phenothiazine Hydrochloride
- 10-[2-(1-Methyl-2-Piperidyl)Ethyl]-2-(Methylthio)-10H-Phenothiazine Hydrochloride
- 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
- 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
- 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride (1:1)
- 10-[3-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine hydrochloride
- 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
- See more synonyms
- 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, hydrochloride (1:1)
- 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride (9CI)
- 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
- 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
- Aldazine
- Labotest-Bb Lt00451961
- Mallorol
- Mellaril
- Mellaril hydrochloride
- Melleretten
- Melleril
- NSC 186060
- Novoridazine
- Orsanil
- Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, hydrochloride
- Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, monohydrochloride
- Ridazin
- Stalleril
- THIORIDAZINEHYDROCHLORIDE,USP
- ThioridazinHCl
- Thioridazine Hcl
- Thioridazinhydrochlorid
- Thioril
- Thiozine
- mellarilhydrochloride
- melleril(tablet)
- usafsz-3
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
- 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
- mellarilhydrochloride
- melleril(tablet)
- usafsz-3
- ThioridazinHCl
- Thioridazinhydrochlorid
- 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
- 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
- Orsanil
- Ridazin
- Stalleril
- 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
- THIORIDAZINEHYDROCHLORIDE,USP
- 10-[3-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine hydrochloride