CAS 130-85-8

Pamoic acid

Description:

Pamoic acid, also known as embonic acid, is an organic compound characterized by its structure as a dicarboxylic acid. It features a naphthalene backbone with two carboxylic acid functional groups, which contributes to its acidic properties. The compound is typically a white to off-white crystalline powder and is sparingly soluble in water, but more soluble in organic solvents such as ethanol and acetone. Pamoic acid is primarily used in the pharmaceutical industry, particularly as a component in the formulation of certain medications, including those for treating parasitic infections. Its ability to form salts and complexes with various drugs enhances their solubility and bioavailability. Additionally, pamoic acid has been studied for its potential applications in drug delivery systems and as a stabilizing agent in various formulations. Due to its chemical structure, it can also exhibit properties such as antimicrobial activity. As with many chemical substances, handling pamoic acid requires appropriate safety measures to mitigate any potential health risks.

Formula: C₂₃H₁₆O₆

InChI: InChI=1/C23H16O6/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h1-10,24-25H,11H2,(H,26,27)(H,28,29)/p-2

InChI key: InChIKey=WLJNZVDCPSBLRP-UHFFFAOYSA-N

SMILES: C(C=1C2=C(C=C(C(O)=O)C1O)C=CC=C2)C=3C4=C(C=C(C(O)=O)C3O)C=CC=C4

Synonyms:

• 2,2-Dihydroxy-1,1-Dinaphthylmethane-3,3-Dicarboxylic Acid
• 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-
• 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-
• 3,3-Dihydroxy-4,4-Methylenedi(2-Naphthoic Acid)
• 4,4'-Methanediylbis(3-Hydroxynaphthalene-2-Carboxylate)
• 4,4'-Methanediylbis(3-Hydroxynaphthalene-2-Carboxylic Acid)
• 4,4-Methylenebis[3-hydroxy-2-naphthalenecarboxylic acid]
• 4,4′-Methylenebis[3-hydroxy-2-naphthoic acid]
• 4-[(3-Carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid
• Bis(2-hydroxy-3-carboxy-1-naphthyl)methane
• Dilithium 4,4'-Methanediylbis(3-Hydroxynaphthalene-2-Carboxylate)
• Embonic acid
• Embonic acid~4,4-Methylenebis(3-hydroxy-2-naphthoic acid)
• Kg 122
• NSC 30188
• NSC 40132
• 4-4'-METHYLENE-BIS-[2-HYDROXY-3-NAPHTHOIC ACID]
• EMBIONIC ACID
• Pamoic
• PAMOIC ACID
• PamoicAcid98%
• PAMOIC ACID FREE ACID
• 2-Naphthalenecarboxylic acid, 4,4-methylenebis3-hydroxy-
• 4-[(3-CARBOXY-2-HYDROXY-NAPHTHALEN-1-YL)METHYL]-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID
• 4,4’-methylenebis(3-hydroxy-2-naphthalenecarboxylicaci
• 4,4'-METHYLENE BIS-(3-HYDROXY-2-NAPTHOIC ACID)
• 4,4’-methylenebis[3-hydroxy-2-naphthalenecarboxylicaci

Pamoic Acid

CAS: 130-85-8

Formula: C₂₃H₁₆O₆

Purity: >96.0%(HPLC)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 388.38

Ref: 3B-P0761

Pamoic acid, 99%

CAS: 130-85-8

Pamoic acid is used in preparation of repository derivatives of medicinal agents, used in pharmacology to increase the solubility of a drug in water. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may r

Formula: C₂₃H₁₆O₆

Purity: 99%

Color and Shape: Crystals or powder or crystalline powder, Yellow to yellow-green

Molecular weight: 388.38

Ref: 02-A15207

Pamoic Acid

CAS: 130-85-8

Carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides etc nesoi

Formula: C₂₃H₁₆O₆

Color and Shape: Yellow Crystalline Powder

Molecular weight: 388.09469

Ref: 45-1493000

2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-

CAS: 130-85-8

Formula: C₂₃H₁₆O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 388.3695

Ref: IN-DA000TV2

Pamoic Acid

CAS: 130-85-8

Pamoic Acid

Purity: 97%

Color and Shape: Powder

Molecular weight: 388.37g/mol

Ref: 54-OR937609

Pamoic acid

CAS: 130-85-8

Formula: C₂₃H₁₆O₆

Purity: (Titration) ≥ 97.0%

Color and Shape: Pale yellow to dark yellow-green powder or crystals

Molecular weight: 388.38

Ref: 7W-GK3917

4,4'-Methylenebis(3-hydroxy-2-naphthoic acid)

CAS: 130-85-8

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 388.375

Ref: 10-F240914

Pamoic Acid

CAS: 130-85-8

Formula: C₂₃H₁₆O₆

Molecular weight: 388.38

Ref: 4Z-P-472001

Pamoic Acid

CAS: 130-85-8

Applications Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases.
References Zhao, P. et al.: Mol. Pharmacol., 78, 560 (2010); Dorjsujen, D. et al.: Nuc. Acids Res., 37, e128 (2009);

Formula: C₂₃H₁₆O₆

Color and Shape: Neat

Molecular weight: 388.37

Ref: TR-P173500

Pamoic acid

CAS: 130-85-8

Pamoic acid is a natural compound that has been found to exhibit antimicrobial activity against a variety of microorganisms. Pamoic acid is also used in the treatment of infectious diseases, such as leprosy, tuberculosis, and AIDS. The biological properties of pamoic acid are due to its ability to bind with peptide hormones and act as a pharmacological agent. Pamoic acid is able to inhibit the synthesis of peptide hormones by binding to their receptors on the cell surface. This inhibition can lead to immunosuppression (e.g., autoimmune diseases) and mitochondrial membrane depolarization. Pamoic acid is also able to bind with benzalkonium chloride, which may account for some of its antimicrobial activity.
Pamoic acid is synthesized from pantothenic acid (vitamin B5) and caproic acid by means of an enzymatic process called transamination.

Formula: C₂₃H₁₆O₆

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 388.37 g/mol

Ref: 3D-FP26746

Pamoic Acid pure, 98%

CAS: 130-85-8

Formula: C₂₃H₁₆O₆

Purity: min. 98%

Color and Shape: White to pale yellow, Crystalline powder, Clear, Yellow

Molecular weight: 388.38

Ref: SR-83162

Pamoic Acid

Controlled Product

CAS: 130-85-8

Formula: C₂₃H₁₆O₆

Color and Shape: Neat

Molecular weight: 388.37

Ref: 86-MM0893.01

Pamoic acid

CAS: 130-85-8

Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.

Formula: C₂₃H₁₆O₆

Purity: 99.99%

Color and Shape: Fine Yellow Powder

Molecular weight: 388.37

Ref: TM-T8353