CAS 130-86-9

Protopine

Description:

Protopine is an alkaloid primarily derived from various plant species, particularly those in the Papaveraceae family, such as the opium poppy. It is characterized by its molecular formula, which typically includes carbon, hydrogen, and nitrogen atoms, reflecting its organic nature. Protopine exhibits a complex structure featuring a fused ring system, which is common among many alkaloids. This compound is known for its potential pharmacological properties, including anti-inflammatory and analgesic effects, although its exact mechanisms of action are still under investigation. Protopine is also recognized for its role in traditional medicine and has been studied for its potential therapeutic applications. In terms of physical properties, it is generally a crystalline solid, and its solubility can vary depending on the solvent used. As with many alkaloids, protopine may exhibit biological activity, making it a subject of interest in both medicinal chemistry and pharmacognosy. However, safety and toxicity profiles should be considered when exploring its applications.

Formula: C₂₀H₁₉NO₅

InChI: InChI=1/C20H19NO5/c1-21-5-4-13-7-18-19(25-10-24-18)8-14(13)16(22)6-12-2-3-17-20(15(12)9-21)26-11-23-17/h2-3,7-8H,4-6,9-11H2,1H3

InChI key: InChIKey=GPTFURBXHJWNHR-UHFFFAOYSA-N

SMILES: CN1CC=2C3=C(C=CC2CC(=O)C=4C(CC1)=CC5=C(C4)OCO5)OCO3

Synonyms:

• 4,6,7,14-Tetrahydro-5-methyl-bis(1,3)benzodioxolo(4,5-c-5',6'-g)azecin-13(5H)-one
• 4,6,7,14-Tetrahydro-5-methylbis[1,3]benzodioxolo[4,5-c:5′,6′-g]azecin-13(5H)-one
• 7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-
• 7-Methyl-2,3:9,10-bis(methylenedioxy)-7,13a-secoberbin-13a-one
• 7-methyl-6,8,9,16-tetrahydrobis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-15(7H)-one
• Ai3-62909
• Biflorine
• Bis(1,3)benzodioxolo(4,5-C:5',6'-g)azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-
• Bis[1,3]benzodioxolo[4,5-c:5′,6′-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-
• Corydinine
• Fumarin
• Fumarine
• Hsdb 3527
• Macleyine
• Protopin
• Protopine
• Protopine (Corydinine)
• 5,7-DIHYDROXY-2-METHYLCHROMONE-6-C-BETA-D-GLUCOPYRANOSIDE
• 5-Methyl-9,10-(methylenedioxy)-4,6,7,13-tetrahydrobenzo[e]-1,3-dioxolo[4,5-l][2]benzazecine-12(5H)-one
• 7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-c:5,6-g]azecin-15(7H)-one
• Protopine USP/EP/BP
• Tangeratin
• Corydalis C
• Hypercorine
• AKOS 243-72
• 6-Methyl-3,4-(methylenebisoxy)-10,11-(methylenebisoxy)-5,6,7,8-tetrahydrodibenzo[c,g]azecine-13(14H)-one
• 4,6,7,14-Tetrahydro-5-Methyl-
• BIFLORIN
• 7-Methyl-6,7,8,9-tetrahydro-[1,3]dioxolo[4',5':5,6]benzo[1,2-c][1,3]dioxolo[5',4':4,5]benzo[1,2-g]azecin-15(16H)-one

Protopine

CAS: 130-86-9

Protopine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₂₀H₁₉NO₅

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 353.48

Ref: 11-1586

Protopine

CAS: 130-86-9

Color and Shape: Neat

Ref: 61-FOR2571.00

4,​6,​7,​14-​Tetrahydro-​5-​methylbis[1,​3]​benzodioxolo[4,​5-​c:5',​6'-​g]​azecin-​13(5H)​-​one

CAS: 130-86-9

Formula: C₂₀H₁₉NO₅

Purity: 99%

Color and Shape: Solid

Molecular weight: 353.3686

Ref: IN-DA000TV1

Protopine

CAS: 130-86-9

Formula: C₂₀H₁₉NO₅

Purity: ≥ 97.0%

Color and Shape: White to off-white or pale yellow-grey powder

Molecular weight: 353.37

Ref: 7W-GY5620

Protopine

CAS: 130-86-9

Formula: C₂₀H₁₉NO₅

Purity: >98.0%(GC)

Color and Shape: White to Light gray to Light yellow powder to crystal

Molecular weight: 353.37

Ref: 3B-P2611

Protopine

CAS: 130-86-9

Formula: C₂₀H₁₉NO₅

Purity: 95%~99%

Molecular weight: 353.374

Ref: BP-BP1158

Protopine

CAS: 130-86-9

Formula: C₂₀H₁₉NO₅

Molecular weight: 353.37

Ref: 4Z-P-361001

Protopine-13C-d3

CAS: 130-86-9

Formula: C₁₉₁₃CH₁₆D₃NO₅

Molecular weight: 357.38

Ref: 4Z-P-361002

Protopine

CAS: 130-86-9

Protopine (Fumarine) is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.

Formula: C₂₀H₁₉NO₅

Purity: 99.25% - 99.45%

Color and Shape: Mon°Clinic Prisms From Alcohol + Chloroform Solid

Molecular weight: 353.37

Ref: TM-T3429

Protopine

CAS: 130-86-9

Natural alkaloid

Formula: C₂₀H₁₉NO₅

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 353.38

Ref: 5G-89546

Protopine

Controlled Product

CAS: 130-86-9

Applications Protopine is a Ca2+ channel blocker and antiplatelet agent (1,2,3). It is also an immunomodulator.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Janbaz, K., et al.: Pharmacol. Res., 38, 215 (1998)(2) Lai, C., et al.: Clin. Chem., 45, 229 (1999)(3) Ma, H., et al.: J. Pharm. Biom. Anal., 49, 440 (2009)

Formula: C₂₀H₁₉NO₅

Color and Shape: Neat

Molecular weight: 353.37

Ref: TR-P838870

Protopine

CAS: 130-86-9

Protopine is a natural compound that has been shown to have anti-inflammatory properties with the ability to inhibit the production of proinflammatory cytokines. This drug has been shown to be effective in vitro and in vivo, and its effects are related to its ability to regulate calcium levels, mitochondrial membrane potential, and neurotrophic factors. Protopine has also been shown to reduce oxidative injury by preventing the oxidation of lipids. The drug can be used for the treatment of inflammatory diseases such as rheumatoid arthritis or osteoarthritis.

Formula: C₂₀H₁₉NO₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 353.37 g/mol

Ref: 3D-FP44455

Protopine-D3

Controlled Product

CAS: 130-86-9

Formula: C₂₀D₃H₁₆NO₅

Color and Shape: Neat

Molecular weight: 356.387

Ref: TR-P838872

Protopine-13CD3

Controlled Product

CAS: 130-86-9

Formula: CC₁₉D₃H₁₆NO₅

Color and Shape: Neat

Molecular weight: 357.38

Ref: TR-P838874