CAS 130-90-5

Cinchonan-9-ol, 6′-methoxy-, (8α,9R)-, monoformate (salt)

Description:

Cinchonan-9-ol, 6′-methoxy-, (8α,9R)-, monoformate (salt), with CAS number 130-90-5, is a chemical compound derived from cinchona alkaloids, which are known for their medicinal properties, particularly in treating malaria. This compound features a cinchonan backbone, characterized by a bicyclic structure that includes a quinoline moiety. The presence of a methoxy group at the 6′ position enhances its pharmacological activity and solubility. The monoformate salt form indicates that the compound is combined with formic acid, which can influence its stability and bioavailability. Typically, such compounds exhibit chiral properties due to the presence of stereocenters, which can affect their interaction with biological targets. In terms of physical properties, cinchonan derivatives often display moderate to high melting points and solubility in organic solvents. The compound's potential applications extend beyond antimalarial activity, possibly including roles in analgesic and anti-inflammatory therapies, owing to the diverse biological activities associated with cinchona alkaloids.

Formula: C₂₀H₂₄N₂O₂·CH₂O₂

InChI: InChI=1S/C20H24N2O2.CH2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;2-1-3/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H,(H,2,3)/t13-,14-,19-,20+;/m0./s1

InChI key: InChIKey=LKUVXQMSYPYURB-DSXUQNDKSA-N

SMILES: [C@@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@]3([N@@]4C[C@H](C=C)[C@](C3)(CC4)[H])[H].C(O)=O

Synonyms:

• Cinchonan-9-ol, 6′-methoxy-, (8α,9R)-, monoformate (salt)
• Formic acid, compd. with (8α,9R)-6′-methoxycinchonan-9-ol (1:1)
• Formic acid, compd. with quinine (1:1)
• Quinaform
• Quinine formiate
• Quinine, formate (1:1) (salt)
• Quinoform
• Quinoform (alkaloid)
• formic acid - (8alpha,9R)-6'-methoxycinchonan-9-ol (1:1)
• Quinine formate

Quinine formate

CAS: 130-90-5

Ref: 7W-GE1461