CAS 1300031-52-0

Benzoic acid, 4-[(2S,4R)-1-acetyl-4-[(4-chlorophenyl)amino]-1,2,3,4-tetrahydro-2-methyl-6-quinolinyl]-

CAS: 1300031-52-0

Formula: C₂₅H₂₃ClN₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 434.9147

Ref: IN-DA000TW8

GSK1324726A

CAS: 1300031-52-0

GSK1324726A

Purity: ≥98%

Molecular weight: 434.91g/mol

Ref: 54-BUP15418

GSK1324726A

CAS: 1300031-52-0

GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).

Formula: C₂₅H₂₃ClN₂O₃

Purity: 98.34% - 99.85%

Color and Shape: Solid

Molecular weight: 434.91

Ref: TM-T6021

GSK1324726A

CAS: 1300031-52-0

GSK1324726A is a small-molecule drug that can be used to treat cancer. It inhibits the HDAC enzyme, which is required for transcriptional repression of genes involved in tumorigenesis. GSK1324726A has been shown to inhibit the expression of suppressor genes and promote apoptosis in myeloid leukemia cells. This drug also potently inhibits HIV replication in vitro and has shown promising results in clinical studies involving patients with AIDS. GSK1324726A binds to bromodomain proteins, which are domains found on histone proteins that bind to acetylated lysine residues on DNA. These domains are known for their ability to regulate gene expression by binding to acetylated lysine residues on histone proteins and blocking transcriptional activation.

Formula: C₂₅H₂₃ClN₂O₃

Purity: Min. 95%

Molecular weight: 434.92 g/mol

Ref: 3D-ACC03152