CAS 130018-87-0: Levocetirizine dihydrochloride

Description:Levocetirizine dihydrochloride is an antihistamine medication primarily used to alleviate symptoms associated with allergic rhinitis and chronic urticaria. It is the active enantiomer of cetirizine, which means it is one of two mirror-image forms of the molecule, specifically the R-enantiomer, known for its enhanced efficacy and reduced side effects. The substance is a white to off-white crystalline powder that is soluble in water, making it suitable for various formulations, including tablets and oral solutions. Levocetirizine acts by selectively inhibiting peripheral H1 receptors, thereby reducing the effects of histamine, a compound involved in allergic reactions. Its pharmacokinetics indicate a rapid onset of action, with a relatively long duration of effect, allowing for once-daily dosing. Common side effects may include drowsiness, fatigue, and dry mouth, although it is generally well-tolerated. Due to its safety profile, it is often preferred for use in both adults and children.

Formula:C₂₁H₂₅ClN₂O₃·2ClH

InChI:InChI=1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H/t21-;;/m1../s1

InChI key:InChIKey=PGLIUCLTXOYQMV-GHVWMZMZSA-N

SMILES:Cl.O=C(O)COCCN1CCN(CC1)C(C=2C=CC=CC2)C3=CC=C(Cl)C=C3

Synonyms:
(R)-(-)-Cetirizine hydrochloride
(R)-Cetirizine dihydrochloride
4-{4-[(S)-(4-Chlorophenyl)(Phenyl)Methyl]Piperazin-1-Yl}Butanoic Acid Hydrochloride (1:1)
Acetic acid, 2-[2-[4-[(R)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2)
Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, dihydrochloride, (R)-
Acetic acid, [2-[4-[(R)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, dihydrochloride
Allear
Allercet
Leocetirizine Hydrochloride
Levo Cetirzine Dihydrochloride
See more synonyms
Levocetirizine 2Hcl
Levocetirizine Dihcl
Levocetirizine Hcl
Levocetirizine Hydrochloride
Levocetrizine Dihydrochloride
Levocetrizine Hydrochloride
Levocetrizinehcl
Levocitirizine 2Hcl
Levocitirizine Dihcl
Levocitirizine Dihydrochloride
Lezyncet
Ucb 28556
Xusal
Xyzal
Xyzall
[2-[4-[(R)-(4-Chlorophenyl)Phenylmethyl]-1-Piperazinyl]Ethoxy]-Acetic Acid Dihydrochloride
Levocetirizine dihydrochloride

Found 11 products.

Product data	Purity	Price range	Estimated delivery
Levocetirizine Dihydrochloride REF: 3B-L0264CAS: 130018-77-8 130018-87-0	>98.0%(T)(HPLC)	44.00 €~111.00 €	Mon 31 Mar 25
Levocetirizine dihydrochloride CRS REF: 41-Y0002401CAS: 130018-87-0	- - -	115.00 €	Thu 03 Apr 25
Levocetirizine Dihydrochloride REF: 45-1359969CAS: 130018-87-0	- - -	447.00 €	Fri 04 Apr 25
Acetic acid, 2-[2-[4-[(R)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2) REF: IN-DA000TX3CAS: 130018-87-0	98%	31.00 €~233.00 €	Mon 07 Apr 25
(R)-Cetirizine DiHCl (Levocetirizine DiHCl) REF: 4Z-C-204CAS: 130018-87-0	- - -	To inquire	Tue 08 Apr 25
Levocetirizine Dihydrochloride REF: 86-MM1035.00-0250CAS: 130018-87-0	- - -	3,841.00 €	Tue 08 Apr 25
Levocetirizine Dihydrochloride REF: TM-T22354CAS: 130018-87-0	99.75%	50.00 €~692.00 €	Tue 08 Apr 25
Levocetirizine dihydrochloride REF: 7W-GP7550CAS: 130018-87-0	98.0 - 102.0 %	130.00 €~377.00 €	Mon 14 Apr 25
Acetic acid, 2-[2-[4-[(R)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2) REF: 10-F861700CAS: 130018-87-0	98%	To inquire	Tue 15 Apr 25
(R)-Cetirizine Dihydrochloride REF: TR-C281106CAS: 130018-87-0	- - -	97.00 €~435.00 €	Tue 15 Apr 25
Levocetirizine dihydrochloride REF: 3D-FL45703CAS: 130018-87-0	Min. 98 Area-%	140.00 €~750.00 €	Mon 19 May 25