CAS 13002-65-8: (E)-Tamoxifen

Description: (E)-Tamoxifen is a synthetic compound primarily used in the treatment and prevention of estrogen receptor-positive breast cancer. It is classified as a selective estrogen receptor modulator (SERM), which means it can act as an estrogen antagonist in breast tissue while exhibiting estrogen-like effects in other tissues, such as bone and the endometrium. The chemical structure of (E)-Tamoxifen features a triphenylethylene backbone, which contributes to its ability to bind to estrogen receptors. It is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. The compound is also characterized by its lipophilicity, which influences its absorption and distribution in the body. Common side effects may include hot flashes, nausea, and an increased risk of thromboembolic events. Due to its mechanism of action, (E)-Tamoxifen has been pivotal in adjuvant therapy for breast cancer and has also been studied for its potential use in other hormone-related conditions.

Formula: C₂₆H₂₉NO

InChI: InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25+

InChI key: InChIKey=NKANXQFJJICGDU-OCEACIFDSA-N

SMILES: O(C1=CC=C(C=C1)C(C=2C=CC=CC2)=C(C=3C=CC=CC3)CC)CCN(C)C

Synonyms:

• (E)-Tamoxifen
• 2-[4-[(1E)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethylethanamine
• Brn 2062021
• Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (E)-
• Ethanamine, 2-[4-[(1E)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-
• Ethanamine, 2-[4-[(1E)-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethyl-
• Ethylamine, 2-[p-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (E)-
• Ethylamine, N,N-dimethyl-2-(p-(1,2-diphenyl-1-butenyl)phenoxy)-, (E)-
• Tamoxifen (E)
• cis-Tamoxifen

Tamoxifen Citrate EP Impurity A ((E)-Tamoxifen)

CAS: 13002-65-8

• Formula: C₂₆H₂₉NO
• Color and Shape: White To Off-White Solid
• Molecular weight: 371.52

(E)-Tamoxifen

CAS: 13002-65-8

• Formula: C₂₆H₂₉NO
• Color and Shape: Neat
• Molecular weight: 371.51

(E)-Tamoxifen

CAS: 13002-65-8

Tamoxifen is a drug that belongs to the group of antiestrogens. It is used in …

• Formula: C₂₆H₂₉NO
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 371.52 g/mol

(E)-Tamoxifen-13C2, 15N

CAS: 13002-65-8

• Formula: C₂C₂₄H₂₉NO
• Color and Shape: Neat
• Molecular weight: 374.493