CAS 130049-85-3
:Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 8 products.
Risperidone EP Impurity C ((R)-Isomer)-d4 ((R)-9-Hydroxy Risperidone-d4, (R)-Paliperidone-d4)
CAS:Formula:C23H23D4FN4O3Color and Shape:Pale Yellow SolidMolecular weight:430.52Risperidone EP Impurity C ((R)-Isomer) ((R)-9-Hydroxy Risperidone, (R)-Paliperidone)
CAS:Formula:C23H27FN4O3Color and Shape:Pale Yellow SolidMolecular weight:426.49(R)-9-Hydroxy Risperidone-d4
CAS:Controlled ProductFormula:C23H23D4FN4O3Color and Shape:NeatMolecular weight:430.51(+)-9-Hydroxyrisperidone
CAS:Controlled Product<p>(+)-9-Hydroxyrisperidone is an active metabolite of risperidone, which is an atypical antipsychotic. It functions as a dopamine (D2) receptor antagonist and serotonin (5-HT2A) receptor antagonist. The (+)-9-hydroxyrisperidone binds to the D2 receptor in the brain and prevents dopamine from binding, thereby blocking dopamine D2 receptors. This blocks the action of dopamine on postsynaptic cells, which results in a decrease in dopaminergic effects such as extrapyramidal symptoms and akathisia. In addition, (+)-9-hydroxyrisperidone binds to serotonin 5-HT2A receptors and blocks serotonin from binding, thereby blocking serotonin effects such as hallucinations and suicidal thoughts.</p>Formula:C23H27FN4O3Purity:Min. 95%Color and Shape:PowderMolecular weight:426.48 g/mol(R)-9-Hydroxy Risperidone
CAS:Controlled Product<p>Applications The R-enantiomer metabolite of Risperidone (R525000), a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),<br></p>Formula:C23H27FN4O3Color and Shape:NeatMolecular weight:426.48
