CAS 13018-54-7

FAICAR

Description:

FAICAR, or 5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, is a chemical compound that plays a significant role in the biosynthesis of purine nucleotides. It is an intermediate in the de novo synthesis pathway of purines, specifically involved in the conversion of ribonucleotides. FAICAR is characterized by its structure, which includes an imidazole ring and a phosphoribosyl moiety, contributing to its biological activity. The compound is typically found in biological systems, particularly in organisms that utilize the purine biosynthetic pathway. Its CAS number, 13018-54-7, is a unique identifier that facilitates the identification and study of this compound in scientific literature and databases. FAICAR's relevance extends to research in biochemistry and molecular biology, where it is studied for its role in cellular metabolism and potential implications in various diseases related to nucleotide metabolism.

Formula: C₁₀H₁₅N₄O₉P

InChI: InChI=1S/C10H15N4O9P/c11-8(18)5-9(13-3-15)14(2-12-5)10-7(17)6(16)4(23-10)1-22-24(19,20)21/h2-4,6-7,10,16-17H,1H2,(H2,11,18)(H,13,15)(H2,19,20,21)/t4-,6-,7-,10-/m1/s1

InChI key: InChIKey=ABCOOORLYAOBOZ-KQYNXXCUSA-N

SMILES: N(C=O)C=1N(C=NC1C(N)=O)[C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O

Synonyms:

• 1H-Imidazole-4-carboxamide, 5-(formylamino)-1-(5-O-phosphono-beta-D-ribofuranosyl)-
• 1H-Imidazole-4-carboxamide, 5-(formylamino)-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-
• 5-(Formylamino)-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-1H-imidazole-4-carboxamide
• 5-(formylamino)-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide
• 5-Formylamino-4-imidazolecarboxamide ribonucleotide
• Faicar
• Imidazole-4-carboxamide, 5-formamido-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 5′-(dihydrogen phosphate)
• 5-(Formylamino)-1-(5-O-phosphono-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide
• 1H-Imidazole-4-carboxamide, 5-(formylamino)-1-(5-O-phosphono-β-D-ribofuranosyl)-
• Imidazole-4-carboxamide, 5-formamido-1-β-D-ribofuranosyl-, 5′-(dihydrogen phosphate)

FAICAR (>80%)

CAS: 13018-54-7

Applications FAICAR is the derivative of AICAR (A611700), which is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

Formula: C₁₀H₁₅N₄O₉P

Purity: >80%

Color and Shape: Neat

Molecular weight: 366.22

Ref: TR-F101065

5-Formylamino-4-imidazolecarboxamide ribonucleotide

CAS: 13018-54-7

5-Formylamino-4-imidazolecarboxamide ribonucleotide is a nucleoside that is synthesized from 5-aminoimidazole ribonucleotide. It has antiviral and anticancer properties and is used as a precursor for the synthesis of other nucleosides. 5-Formylamino-4-imidazolecarboxamide ribonucleotide can be used in the preparation of oligodeoxyribonucleotides, which are involved in DNA replication, transcription, and translation. This compound also has been shown to inhibit the growth of cells with HIV or cancerous cells.

Formula: C₁₀H₁₅N₄O₉P

Purity: (Elemental Analysis) Min. 85%

Molecular weight: 366.22 g/mol

Ref: 3D-NF182019

FAICAR

CAS: 13018-54-7

FAICAR (5-Formamidoimidazole-4-carboxamide ribotide), a purine nucleotide, plays a crucial role in metabolic processes.

Formula: C₁₀H₁₅N₄O₉P

Color and Shape: Solid

Molecular weight: 366.22

Ref: TM-T84746