CAS 130194-43-3

(S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE HYDROCHLORIDE

Description:

(S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine hydrochloride is a chiral organic compound characterized by its specific stereochemistry, indicated by the (S) configuration. This compound features a propylamine backbone with a phenyl group and a 4-trifluoromethyl-phenoxy substituent, which contributes to its unique chemical properties. The presence of the trifluoromethyl group enhances lipophilicity and may influence biological activity, making it of interest in pharmaceutical applications. As a hydrochloride salt, it is typically more soluble in water compared to its free base form, facilitating its use in various formulations. The compound's molecular structure suggests potential interactions with biological targets, which could be explored in medicinal chemistry. Its CAS number, 130194-43-3, allows for easy identification in chemical databases. Overall, this compound exemplifies the complexity and specificity often found in drug design, particularly in the context of developing selective agents for therapeutic purposes.

Formula: C₁₆H₁₆F₃NO

InChI: InChI=1/C16H16F3NO/c17-16(18,19)13-6-8-14(9-7-13)21-15(10-11-20)12-4-2-1-3-5-12/h1-9,15H,10-11,20H2/t15-/m1/s1

SMILES: c1ccc(cc1)[C@@H](CCN)Oc1ccc(cc1)C(F)(F)F

Synonyms:

• (S)-3-[4-(Trifluoromethyl)Phenoxy]-3-Phenylpropan-1-Amine Hydrochloride
• (3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine

Benzenepropanamine, γ-[4-(trifluoromethyl)phenoxy]-, (γR)-

CAS: 130194-43-3

Formula: C₁₆H₁₆F₃NO

Color and Shape: Liquid

Molecular weight: 295.2995

Ref: IN-DA000U3Q

1-[(1R)-3-Amino-1-phenylpropoxy]-4-(trifluoromethyl)benzene

CAS: 130194-43-3

1-[(1R)-3-Amino-1-phenylpropoxy]-4-(trifluoromethyl)benzene

Molecular weight: 295.29955g/mol

Ref: 54-PC106470

(R)-Norfluoxetine

Controlled Product

CAS: 130194-43-3

Applications A metabolite of Fluoxetine (F597100), a selective serotonin reuptake inhibitor which is used as an antidepressant.
References Wong, D., et al.: J. Pharmacol. Exp. Ther., 193, 804 (1975), Thorsen, T., et al.: J. Cancer Clin. Oncol., 18, 333 (1982), Howell, A., et al.: Lancet, 365, 60 (2005),

Formula: C₁₆H₁₆F₃NO

Color and Shape: Neat

Molecular weight: 295.30

Ref: TR-N681090

(gammaR)-gamma-[4-(Trifluoromethyl)Phenoxy]-Benzenepropanamine

CAS: 130194-43-3

(gammaR)-gamma-[4-(Trifluoromethyl)Phenoxy]-Benzenepropanamine is a drug that has been shown to be clinically effective in the treatment of depression. It is an antidepressant that inhibits serotonin reuptake and inhibits uptake. The effects of this drug on the human liver have yet to be determined. (gammaR)-gamma-[4-(Trifluoromethyl)Phenoxy]-Benzenepropanamine has been shown to have a matrix effect in clinical trials, and its efficacy was statistically significant when compared to other drugs. This drug binds with high affinity to the serotonin transporter and blocks the uptake of serotonin into cells, thereby increasing levels of serotonin in the synaptic cleft. Magnetic resonance spectroscopy has revealed that (gammaR)-gamma-[4-(Trifluoromethyl)Phenoxy]-Benzenepropanamine enantiomers bind differently to the serotonin

Formula: C₁₆H₁₆F₃NO

Purity: Min. 95%

Molecular weight: 295.3 g/mol

Ref: 3D-FG96959

(R)-Norfluoxetine

CAS: 130194-43-3

(R)-Norfluoxetine is the (R)-enantiomer of Norfluoxetine. It functions as a potent serotonin reuptake inhibitor, with a Ki value of 13 nM. This compound is utilized in the research of depression.

Formula: C₁₆H₁₆F₃NO

Color and Shape: Solid

Molecular weight: 295.299

Ref: TM-T204202