CAS 130209-82-4

Latanoprost

Description:

Latanoprost is a synthetic prostaglandin analog primarily used in the treatment of glaucoma and ocular hypertension. It functions by increasing the outflow of aqueous humor, thereby reducing intraocular pressure. The substance is characterized by its ability to selectively bind to the prostaglandin F2α receptor, which plays a crucial role in its mechanism of action. Latanoprost is typically administered as an ophthalmic solution, and its formulation often includes preservatives to enhance stability and shelf life. The compound is known for its relatively high lipophilicity, allowing it to penetrate ocular tissues effectively. Common side effects may include eye redness, changes in iris pigmentation, and eyelash growth. Latanoprost is generally well-tolerated, but it is contraindicated in patients with a history of hypersensitivity to the drug or its components. Its pharmacokinetics involve rapid absorption and metabolism, with a half-life that supports once-daily dosing, making it a convenient option for patients managing chronic eye conditions.

Formula: C₂₆H₄₀O₅

InChI: InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22+,23+,24-,25+/m0/s1

InChI key: InChIKey=GGXICVAJURFBLW-CEYXHVGTSA-N

SMILES: C(/C=C\CCCC(OC(C)C)=O)[C@@H]1[C@@H](CC[C@H](CCC2=CC=CC=C2)O)[C@H](O)C[C@@H]1O

Synonyms:

• 5-Heptenoic acid, 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl]-, 1-methylethyl ester, [1R-[1α(Z),2β(R*),3α,5α]]-
• PhXA 41
• XA 41
• Latanoprost
• 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-, 1-methylethyl ester, (5Z)-

Latanoprost

CAS: 130209-82-4

Formula: C₂₆H₄₀O₅

Purity: >98.0%(HPLC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 432.60

Ref: 3B-L0262

LATANOPROST CRS

CAS: 130209-82-4

LATANOPROST CRS

Ref: 41-Y0002218

Latanoprost

CAS: 130209-82-4

Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues

Formula: C₂₆H₄₀O₅

Color and Shape: Yellow Liquid Oil

Molecular weight: 432.28757

Ref: 45-1357475

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-, 1-methylethyl ester, (5Z)-

CAS: 130209-82-4

Formula: C₂₆H₄₀O₅

Purity: 97%

Color and Shape: Liquid

Molecular weight: 432.5928

Ref: IN-DA000U58

Latanoprost

CAS: 130209-82-4

Formula: C₂₆H₄₀O₅

Color and Shape: Colorless Liquid

Molecular weight: 432.61

Ref: 4Z-L-321

Latanoprost (0.10% wt/v in ETHANOL), min. 98%

CAS: 130209-82-4

Formula: C₂₆H₄₀O₅

Purity: min. 98%

Color and Shape: Colorless to Yellowish Oil (SOLUTION IN 10% ETHANOL)

Molecular weight: 432.59

Ref: 08-06-6012

Latanoprost

CAS: 130209-82-4

Latanoprost

Purity: ≥98%

Molecular weight: 432.59g/mol

Ref: 54-BUP12359

Latanoprost

CAS: 130209-82-4

Formula: C₂₆H₄₀O₅

Purity: ≥ 99.0%

Color and Shape: Colourless to light yellow liquid

Molecular weight: 432.59

Ref: 7W-GP3013

Latanoprost

Controlled Product

CAS: 130209-82-4

Formula: C₂₆H₄₀O₅

Color and Shape: Neat

Molecular weight: 432.59

Ref: 04-CA14593150

Latanoprost

Controlled Product

CAS: 130209-82-4

Formula: C₂₆H₄₀O₅

Color and Shape: Neat

Molecular weight: 432.59

Ref: 86-MM3316.00

Latanoprost

CAS: 130209-82-4

Latanoprost (Xalatan) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect.

Formula: C₂₆H₄₀O₅

Purity: 99.69% - 99.89%

Color and Shape: Pale Yellow Oil

Molecular weight: 432.59

Ref: TM-T2528

Latanoprost

CAS: 130209-82-4

Applications Prostaglandin analog, used to treat glaucoma and other degenerative diseases of the eye.
References Rhee, D.J., et al.: Clinic. Ophthalmol., 2, 313 (2008), Hernandez, M., et al.: Exp. Eye Res., 86, 798 (2008), Nagata, T., et al.: J. Pharmacol. Sci., 106, 423 (2008), Ikeda, Y., et al.: J. Ocular Pharmacol. Ther., 24, 230 (2008),

Formula: C₂₆H₄₀O₅

Color and Shape: Light Yellow

Molecular weight: 432.59

Ref: TR-L177280

Latanoprost

CAS: 130209-82-4

Agonist of FP prostaglandin receptor, EP1 and EP3 prostaglandin receptors

Formula: C₂₆H₄₀O₅

Purity: Min. 98 Area-%

Color and Shape: Clear Liquid

Molecular weight: 432.59 g/mol

Ref: 3D-FL24849

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-, 1-methylethyl ester, (5Z)-

CAS: 130209-82-4

Purity: 99%

Molecular weight: 432.6010132

Ref: 10-F861701

Latanoprost-d4

Controlled Product

CAS: 130209-82-4

Formula: C₂₆H₃₆D₄O₅

Color and Shape: Neat

Molecular weight: 436.60

Ref: TR-L177282