CAS 1303420-67-8

6-Fluoro-N-((5-Fluoro-2-Methoxypyridin-3-Yl)Methyl)-5-((5-Methyl-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Methyl)Pyridin-2-Amine

CAS: 1303420-67-8

6-Fluoro-N-((5-Fluoro-2-Methoxypyridin-3-Yl)Methyl)-5-((5-Methyl-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Methyl)Pyridin-2-Amine

Purity: 98%

Molecular weight: 395.41g/mol

Ref: 54-PC108529

PLX5622

CAS: 1303420-67-8

PLX5622

Purity: ≥98%

Molecular weight: 395.41g/mol

Ref: 54-BUP15087

PLX5622

CAS: 1303420-67-8

PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination of microglia. Cost effective and quality assured.

Formula: C₂₁H₁₉F₂N₅O

Purity: 98% - 99.92%

Color and Shape: Solid

Molecular weight: 395.41

Ref: TM-T7100

PLX5622

CAS: 1303420-67-8

PLX5622 is a small molecule that binds to the integrin receptor, which is a calcium-binding protein. It has shown efficacy in suppressing chronic oral irritation and restoring locomotor activity in animals. PLX5622 also reduces microglial activation and neuronal death. This drug also blocks the response of cells to colony-stimulating factor (CSF) by inhibiting CSF binding to its receptors on the cell surface. The effects of PLX5622 have been tested using fluorescein angiography and histological analysis in rats with experimental glaucoma.

Formula: C₂₁H₁₉F₂N₅O

Purity: Min. 95%

Molecular weight: 395.41 g/mol

Ref: 3D-DCC42067