CAS 130349-07-4

N-hydroxypentamidine

Description:

N-hydroxypentamidine is a chemical compound characterized by its hydroxylamine functional group attached to the pentamidine structure. It is primarily known for its potential applications in medicinal chemistry, particularly in the treatment of various parasitic infections, including those caused by Trypanosoma species. The compound exhibits properties typical of hydroxypamidines, such as the ability to form hydrogen bonds, which can enhance its interaction with biological targets. N-hydroxypentamidine is also noted for its potential to modulate biological pathways, making it a subject of interest in drug development. Its molecular structure contributes to its solubility and stability, which are critical factors in pharmacokinetics. Additionally, the compound's safety profile and toxicity are important considerations in its therapeutic applications. As with many chemical substances, further research is necessary to fully elucidate its mechanisms of action and optimize its use in clinical settings.

Formula: C₁₉H₂₄N₄O₃

InChI: InChI=1/C19H24N4O3/c20-18(21)14-4-8-16(9-5-14)25-12-2-1-3-13-26-17-10-6-15(7-11-17)19(22)23-24/h4-11,24H,1-3,12-13H2,(H3,20,21)(H2,22,23)

SMILES: C(CCOc1ccc(cc1)C(=N)N)CCOc1ccc(cc1)C(=NO)N

Synonyms:

• Benzenecarboximidamide, 4-((5-(4-(aminoiminomethyl)phenoxy)pentyl)oxy)-N-hydroxy-
• 4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}-N'-hydroxybenzenecarboximidamide
• N-Hydroxypentamidine
• 1-(4'-HydroxyaMidinophenoxy)-5-(4'-aMidinophenoxy)pentane
• 4-[[5-[4-(AMinoiMinoMethyl)phenoxy]pentyl]oxy]-N-hydroxybenzenecarboxiMidaMide
• N-Hydroxy Pentamidine Acetate (salt)
• 4-[[5-[4-[Amino(hydroxyimino)methyl]phenoxy]pentyl]oxy]benzamidine
• PentaMidine AMidoxiMe

N-Hydroxy Pentamidine Acetate

CAS: 130349-07-4

Formula: C₁₉H₂₄N₄O₃C₂H₄O₂

Color and Shape: White To Off-White Solid

Molecular weight: 356.43 2/3 *60.05

Ref: 4Z-P-155001

Pentamidine Amidoxime

Controlled Product

CAS: 130349-07-4

Applications Pentamidine Monoxime is an amidoxime metabolite of Pentamidine (P272500).
References Clement, B. et al.: Arzneim.-Forsch., 35, 1009 (1985); Atsriku, C. et al.: Chem.-Biol. Inter., 146, 297 (2003); Clement, B. et al.: ARrh. Pharm., 325, 61 (1992);

Formula: C₁₉H₂₄N₄O₃

Color and Shape: Neat

Molecular weight: 356.419

Ref: TR-P272510