Exendin-3 is a peptide that is derived from the saliva of the Gila monster, a lizard native to the southwestern United States. It is a 39-amino acid long molecule and is known for its role as a glucagon-like peptide-1 (GLP-1) receptor agonist. This characteristic makes Exendin-3 significant in the regulation of glucose metabolism and appetite control, which has implications for diabetes treatment and obesity management. The peptide exhibits high affinity for the GLP-1 receptor, promoting insulin secretion in response to glucose levels, and has a longer half-life compared to endogenous GLP-1 due to its resistance to enzymatic degradation. Exendin-3 is often studied in the context of diabetes research and has been utilized in various experimental models to explore its therapeutic potential. Its chemical structure includes specific modifications that enhance its stability and biological activity, making it a valuable compound in pharmacological studies.

Exendin 3

130391-54-7: Exendin-3 is a peptide that is derived from the saliva of the Gila monster, a lizard native to the southwestern United States. It is a 39-amino acid long molecule and is known for its role as a glucagon-like peptide-1 (GLP-1) receptor agonist. This characteristic makes Exendin-3 significant in the regulation of glucose metabolism and appetite control, which has implications for diabetes treatment and obesity management. The peptide exhibits high affinity for the GLP-1 receptor, promoting insulin secretion in response to glucose levels, and has a longer half-life compared to endogenous GLP-1 due to its resistance to enzymatic degradation. Exendin-3 is often studied in the context of diabetes research and has been utilized in various experimental models to explore its therapeutic potential. Its chemical structure includes specific modifications that enhance its stability and biological activity, making it a valuable compound in pharmacological studies.

CAS 130391-54-7

Exendin 3