CAS 130405-40-2

(-)-catechin gallate

Description:

(-)-Catechin gallate, with the CAS number 130405-40-2, is a polyphenolic compound primarily found in various plants, particularly in green tea. It is a type of flavonoid, specifically a catechin, which is known for its antioxidant properties. This compound exhibits a complex structure that includes a catechin backbone with a gallate moiety, contributing to its biological activity. (-)-Catechin gallate is recognized for its potential health benefits, including anti-inflammatory, anti-cancer, and cardioprotective effects. It is soluble in water and organic solvents, making it versatile for various applications in food, pharmaceuticals, and cosmetics. The compound's stability can be influenced by factors such as pH and temperature, and it may undergo oxidation when exposed to air. Research continues to explore its mechanisms of action and potential therapeutic uses, particularly in the context of chronic diseases. Overall, (-)-catechin gallate is an important compound in the field of natural products and health sciences, reflecting the growing interest in plant-derived substances for health promotion.

Formula: C₂₂H₁₈O₁₀

InChI: InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21+/m1/s1

InChI key: InChIKey=LSHVYAFMTMFKBA-CTNGQTDRSA-N

SMILES: O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@H]2[C@@H](OC=3C(C2)=C(O)C=C(O)C3)C4=CC(O)=C(O)C=C4

Synonyms:

• (-)-Catechin 3-O-gallate
• (-)-Catechin 3-gallate
• (2S,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
• Benzoic acid, 3,4,5-trihydroxy-, (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester
• Benzoic acid, 3,4,5-trihydroxy-, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, (2S-trans)-
• Ccris 9303
• (-)-Catechin gallate
• Chorionic gonadotrophin chain β
• (-)-Catechin gallate ((-)-Catechin 3-gallate
• Choriogonadotropin subunit β
• (-)-Catechin gallate(CG)
• (-)-Catechin gallate, 98%, from Green tea
• Anti-HCG β, C-Terminal antibody produced in rabbit
• (2S,3R)-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-1(2H)-BENZOPYRAN-3,5,7-TRIOL 3-(3,4,5-TRIHYDROXYBENZOATE)
• (-)-CG
• 3,4,5-Trihydroxybenzoic Acid (2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl Ester
• BCatechin gallate
• ()-Catechin gallate,(2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate)
• ()-Catechin gallat
• ()-Catechin gallate, >=98%
• (2S,3R)-2-(3,4-Dihydroxyphenyl)-3-(3,4,5-trihydroxybenzoyloxy)-3,4-dihydro-2H-1-benzopyran-5,7-diol
• (2S,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroMan-3-yl 3,4,5-trihydroxybenzoate
• 3,4,5-Trihydroxybenzoic acid [[(2S)-2β-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran]-3α-yl] ester
• Catechin gallate/(-)-Catechin gallate
• Catechin gallate CG (-)-Catechin gallate
• ANTI-CG antibody produced in mouse

(-) Catechin gallate

CAS: 130405-40-2

(-) Catechin gallate analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₂H₁₈O₁₀

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 442.38

Ref: 11-0972S

Benzoic acid, 3,4,5-trihydroxy-, (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester

CAS: 130405-40-2

Formula: C₂₂H₁₈O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 442.3723

Ref: IN-DA000UDI

(-)-Catechin gallate

CAS: 130405-40-2

(-)-Catechin gallate

Purity: ≥95%

Molecular weight: 442.37g/mol

Ref: 54-BUP07425

Catechin gallate

CAS: 130405-40-2

Catechin gallate is a minor constituent in green tea catechins, it inhibits the activity of COX-1 and COX-2 enzymes. Catechin gallate (IC50=53 microM) shows cytotoxicity against the colorectal adenocarcinoma cell line HCT116, it also exhibits strong anti-proliferative and anti-inflammatory activities on pancreatic ductal adenocarcinoma (PDAC) cells. Catechin 3-gallate is a good inhibitor of maltase, with IC50 values of 62 uM, it inhibits both α-glucosidases and rabbit glycogen phosphorylase (GP) in vitro and in cell culture, would contribute to the protection or improvement of type 2 diabetes.

Formula: C₂₂H₁₈O₁₀

Purity: 95%~99%

Molecular weight: 442.376

Ref: BP-BP0323

(-)-Catechin gallate

CAS: 130405-40-2

Formula: C₂₂H₁₈O₁₀

Molecular weight: 442.37

Ref: 7W-GK9244

(-)-Catechin gallate

CAS: 130405-40-2

(-)-Catechin gallate inhibits 6PGD, IDH, Beta-secretase, and fights chloroquine-sensitive/resistant Plasmodium falciparum.

Formula: C₂₂H₁₈O₁₀

Purity: 97.74% - >99.99%

Color and Shape: Solid

Molecular weight: 442.37

Ref: TM-T3682

(-)-catechin 3-gallate

CAS: 130405-40-2

Oxygen-heterocyclic compound

Formula: C₂₂H₁₈O₁₀

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 442.38

Ref: 5G-82497

(-)-Catechin Gallate

Controlled Product

CAS: 130405-40-2

Applications A major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor.
References Van Aller, G., et al.: Biochem. Biophys. Res. Commun., 406, 194 (2011),

Formula: C₂₂H₁₈O₁₀

Color and Shape: Neat

Molecular weight: 442.37

Ref: TR-C217510

Benzoic acid, 3,4,5-trihydroxy-, (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester

CAS: 130405-40-2

Purity: 98%

Molecular weight: 442.3760071

Ref: 10-F861685

(-)-Catechin gallate

CAS: 130405-40-2

(-)-Catechin gallate is a flavonoid that belongs to the group of polyphenols. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. (-)-Catechin gallate has shown protective effects on skin cells against ultraviolet-induced skin cancer and energy metabolism, as well as anti-inflammatory properties. This compound also inhibits the release of pro-inflammatory mediators by inhibiting P2Y receptors. (-)-Catechin gallate may have chemopreventive effects by blocking signaling pathways involved in colorectal adenocarcinoma, squamous carcinoma, and human serum.

Formula: C₂₂H₁₈O₁₀

Purity: Min. 95%

Molecular weight: 442.37 g/mol

Ref: 3D-FC19836