CAS 13042-18-7

Fendiline

Description:

Fendiline is a chemical compound primarily recognized for its use as a calcium channel blocker, which is utilized in the treatment of hypertension and certain cardiac conditions. It is classified as a phenylalkylamine derivative and exhibits properties that allow it to inhibit the influx of calcium ions through voltage-gated calcium channels in cardiac and vascular smooth muscle. This action leads to vasodilation and a reduction in blood pressure. Fendiline is characterized by its relatively low solubility in water, which can affect its bioavailability and pharmacokinetics. The compound has a moderate molecular weight and features a specific arrangement of functional groups that contribute to its pharmacological activity. Additionally, it has been studied for its potential neuroprotective effects, although its clinical use may be limited due to side effects or the availability of alternative treatments. As with any pharmaceutical agent, understanding its mechanism of action, side effects, and interactions with other medications is crucial for safe and effective use.

Formula: C₂₃H₂₅N

InChI: InChI=1S/C23H25N/c1-19(20-11-5-2-6-12-20)24-18-17-23(21-13-7-3-8-14-21)22-15-9-4-10-16-22/h2-16,19,23-24H,17-18H2,1H3

InChI key: InChIKey=NMKSAYKQLCHXDK-UHFFFAOYSA-N

SMILES: C(CCNC(C)C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3

Synonyms:

• 13042-18-7
• 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine
• Benzenepropanamine, .gamma.-phenyl-N-(1-phenylethyl)-
• Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)-
• Benzylamine, N-(3,3-diphenylpropyl)-α-methyl-
• Difmecor
• Fendilin
• N-(1-Phenylethyl)-3,3-diphenylpropylamine
• N-(3,3-Diphenylpropyl)-a-methylbenzylamine
• Phendilin
• dl-Fendiline
• g-Phenyl-N-(1-phenylethyl)benzenepropanamine

Fendiline

CAS: 13042-18-7

Fendiline: coronary vasodilator, calcium blocker, potential antiarrhythmic/antianginal.

Formula: C₂₃H₂₅N

Color and Shape: Solid

Molecular weight: 315.45

Ref: TM-T71021