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CAS 13045-94-8

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D-Melphalan

Description:
D-Melphalan, also known as D-phenylalanine mustard, is a synthetic alkylating agent primarily used in the treatment of certain types of cancer, particularly multiple myeloma and ovarian cancer. It is a derivative of the amino acid phenylalanine and belongs to the class of nitrogen mustards. D-Melphalan exhibits cytotoxic properties by forming cross-links in DNA, which inhibits cell division and leads to cell death. The compound is typically administered intravenously or orally and is known for its ability to penetrate tissues effectively. Its chemical structure includes a phenylalanine moiety linked to a mustard group, contributing to its reactivity. While it can be effective in cancer therapy, D-Melphalan is associated with various side effects, including myelosuppression, gastrointestinal disturbances, and potential long-term risks such as secondary malignancies. Due to its potent effects, careful monitoring and dosage adjustments are essential during treatment. Overall, D-Melphalan represents a significant therapeutic option in oncology, particularly for patients with specific malignancies.
Formula:C13H18Cl2N2O2
InChI:InChI=1/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m1/s1
InChI key:InChIKey=SGDBTWWWUNNDEQ-GFCCVEGCSA-N
SMILES:N(CCCl)(CCCl)C1=CC=C(C[C@H](C(O)=O)N)C=C1
Synonyms:
  • (R)-2-Amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoicacid
  • 4-[Bis(2-chloroethyl)amino]-<span class="text-smallcaps">D</span>-phenylalanine
  • <span class="text-smallcaps">D</span>-Melphalan
  • <span class="text-smallcaps">D</span>-Phenylalanine mustard
  • <span class="text-smallcaps">D</span>-Phenylalanine, 4-[bis(2-chloroethyl)amino]-
  • Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, D-
  • Alanine, 3-[p-[bis(2-chloroethyl)amino]phenyl]-, <span class="text-smallcaps">D</span>-
  • Cb 3026
  • D-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine
  • D-Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-
  • See more synonyms
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Found 3 products.
  • (R)-2-Amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoic acid
    Indagoo
    + Info

    (R)-2-Amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoic acid

    CAS:
    Formula:C13H18Cl2N2O2
    Color and Shape:Solid
    Molecular weight:305.2002

    Ref: IN-DA000UGM

    ne
    To inquire
  • Melphalan D-Isomer
    TLC
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    Melphalan D-Isomer

    CAS:
    Formula:C13H18Cl2N2O2
    Color and Shape:White To Off-White Solid
    Molecular weight:305.20

    Ref: 4Z-M-8516

    5mg
    To inquire
    10mg
    910.00€
    25mg
    1,638.00€
    50mg
    2,366.00€
    100mg
    To inquire
  • D-Melphalan
    TRC
    + Info

    D-Melphalan

    Controlled Product
    CAS:

    Stability Hygroscopic
    Applications D-Melphalan is an isomer of melphalan (M216900), which is an antineoplastic.
    Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
    References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966), Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980),

    Formula:C13H18Cl2N2O2
    Color and Shape:Neat
    Molecular weight:305.2

    Ref: TR-M216915

    1mg
    177.00€