CAS 130466-38-5

Methanesulfonamide, N-[2-[(2R,12bS)-1,3,4,6,7,12b-hexahydro-2′-oxospiro[2H-benzofuro[2,3-a]quinolizine-2,4′-imidazolidin]-3′-yl]ethyl]-, hydrochloride (1:1)

Description:

Methanesulfonamide, N-[2-[(2R,12bS)-1,3,4,6,7,12b-hexahydro-2′-oxospiro[2H-benzofuro[2,3-a]quinolizine-2,4′-imidazolidin]-3′-yl]ethyl]-, hydrochloride (1:1), with CAS number 130466-38-5, is a chemical compound characterized by its complex structure, which includes a spirocyclic framework and an imidazolidine moiety. This compound is a hydrochloride salt, indicating that it is soluble in water and may exhibit different properties compared to its free base form. Methanesulfonamide derivatives are often recognized for their potential biological activity, including antimicrobial and anti-inflammatory properties. The presence of the hexahydro and benzofuroquinolizine structures suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Additionally, the specific stereochemistry (2R,12bS) indicates that the compound may exhibit chirality, which can influence its pharmacological effects. Overall, this compound's unique structural features and potential biological activities make it a subject of interest for further research and development in pharmaceutical applications.

Formula: C₂₀H₂₆N₄O₄S·ClH

InChI: InChI=1S/C20H26N4O4S.ClH/c1-29(26,27)22-8-11-24-19(25)21-13-20(24)7-10-23-9-6-15-14-4-2-3-5-17(14)28-18(15)16(23)12-20;/h2-5,16,22H,6-13H2,1H3,(H,21,25);1H/t16-,20+;/m0./s1

InChI key: InChIKey=UTMOWVIYZQWJHT-VASSOYJASA-N

SMILES: C(CNS(C)(=O)=O)N1[C@]2(C[C@]3(C4=C(C=5C(O4)=CC=CC5)CCN3CC2)[H])CNC1=O.Cl

Synonyms:

• Spiro[2H-benzofuro[2,3-a]quinolizine-2,4′-imidazolidine], methanesulfonamide deriv.
• MK 467
• Methanesulfonamide, N-[2-[(2R,12bS)-1,3,4,6,7,12b-hexahydro-2′-oxospiro[2H-benzofuro[2,3-a]quinolizine-2,4′-imidazolidin]-3′-yl]ethyl]-, monohydrochloride
• Methanesulfonamide, N-[2-[(2R,12bS)-1,3,4,6,7,12b-hexahydro-2′-oxospiro[2H-benzofuro[2,3-a]quinolizine-2,4′-imidazolidin]-3′-yl]ethyl]-, hydrochloride (1:1)
• Methanesulfonamide, N-[2-(1,3,4,6,7,12b-hexahydro-2′-oxospiro[2H-benzofuro[2,3-a]quinolizine-2,4′-imidazolidin]-3′-yl)ethyl]-, monohydrochloride, (2R-trans)-

Vatinoxan hydrochloride

CAS: 130466-38-5

Vatinoxan hydrochloride is a drug that belongs to the class of α2-adrenergic receptor antagonists. It is used to treat hypertension and congestive heart failure in dogs, cats and horses. Vatinoxan hydrochloride is a potent α2-adrenergic receptor antagonist with clinical relevance for humans. It has been shown to increase plasma glucose levels in anesthetized dogs by acting on cardiac alpha-2 adrenoceptors, which may be responsible for its therapeutic effects in patients with angina pectoris. The pharmacokinetic properties of this drug are not well understood yet, but it has been shown to have similar effects as dobutamine on blood pressure and cardiac function in animals.

Formula: C₂₀H₂₆N₄O₄S•HCl

Purity: Min. 95%

Molecular weight: 455 g/mol

Ref: 3D-FFA46638

Vatinoxan hydrochloride

CAS: 130466-38-5

Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.

Formula: C₂₀H₂₇ClN₄O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 454.97

Ref: TM-T13285