CAS 13048-95-8

N(4), O(2')-dimethylcytidine

Description:

N(4), O(2')-dimethylcytidine, with the CAS number 13048-95-8, is a modified nucleoside derived from cytidine, which is one of the building blocks of RNA. This compound features two methyl groups: one attached to the nitrogen atom at the 4-position of the pyrimidine ring and another at the oxygen atom of the 2' hydroxyl group of the ribose sugar. These modifications can influence the stability, structure, and function of RNA molecules, potentially affecting their interactions with proteins and other nucleic acids. N(4), O(2')-dimethylcytidine is of interest in biochemical and pharmaceutical research, particularly in the study of RNA modifications and their roles in gene expression and regulation. Its unique structural characteristics may also contribute to its potential applications in therapeutic contexts, such as in the development of RNA-based drugs or as a tool in molecular biology. Overall, this compound exemplifies the diverse modifications that nucleosides can undergo, impacting their biological functions.

Formula: C₁₁H₁₇N₃O₅

InChI: InChI=1/C11H17N3O5/c1-12-7-3-4-14(11(17)13-7)10-9(18-2)8(16)6(5-15)19-10/h3-4,6,8-10,15-16H,5H2,1-2H3,(H,12,13,17)/t6-,8-,9-,10-/m1/s1

SMILES: CN=c1ccn([C@H]2[C@@H]([C@@H]([C@@H](CO)O2)O)OC)c(n1)O

Synonyms:

• Cytidine, N-methyl-2'-O-methyl-
• N-methyl-2'-O-methylcytidine

N4-Methyl-2’-O-methyl-cytidine

CAS: 13048-95-8

Formula: C₁₁H₁₇N₃O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 271.2698

Ref: IN-DA000UHY

1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-4-(methylamino)pyrimidin-2(1H)-one

CAS: 13048-95-8

1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-4-(methylamino)pyrimidin-2(1H)-one

Purity: 97%

Molecular weight: 271.27g/mol

Ref: 54-OR1068864

N4-Methyl-2'-O-methyl-cytidine

CAS: 13048-95-8

Nucleosides and Reagents - 2’-O-Methyl nucleoside

Formula: C₁₁H₁₇N₃O₅

Color and Shape: Solid

Molecular weight: 271.27

Ref: TM-TNU0125

N4-Methyl-2'-O-methyl-cytidine

CAS: 13048-95-8

N4-Methyl-2'-O-methyl-cytidine is a nucleoside analog that is used as an antibiotic. The ribosomal RNA in prokaryotes has been found to be sensitive to this drug, which inhibits protein synthesis by reversibly binding to the 50S subunit of the ribosome and inhibiting translocation. N4-Methyl-2'-O-methyl-cytidine also binds to the ribonucleoprotein in eukaryotic cells, blocking translation of mRNA into proteins. N4-Methyl-2'-O-methyl-cytidine is effective against Gram positive bacteria, such as Staphylococcus aureus and Clostridium perfringens, while being inactive against Gram negative bacteria. This drug has a molecular weight of 197 and can be broken down into low molecular weight fragments or high molecular weight fragments.

Formula: C₁₁H₁₇N₃O₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 271.27 g/mol

Ref: 3D-NM144592