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CAS 130493-03-7

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bimoclomol

Description:
Bimoclomol is a chemical compound recognized for its role as a pharmacological agent, particularly in neuroprotection and as a potential treatment for various neurodegenerative conditions. It is classified as a small molecule and is known to exhibit properties that enhance cellular stress responses, particularly in the context of heat shock proteins. Bimoclomol acts by modulating the expression of these proteins, which play a crucial role in protecting cells from damage caused by stressors such as oxidative stress and inflammation. The compound has been studied for its potential therapeutic effects in conditions like Alzheimer's disease and other neurodegenerative disorders. Additionally, bimoclomol has shown promise in promoting cell survival and improving cognitive function in preclinical models. Its mechanism of action involves the activation of heat shock factor 1 (HSF1), leading to increased synthesis of heat shock proteins. Overall, bimoclomol represents a significant area of interest in medicinal chemistry and neuropharmacology due to its unique properties and potential applications in treating neurological diseases.
Formula:C14H20ClN3O2
InChI:InChI=1/C14H20ClN3O2/c15-14(12-5-4-6-16-9-12)17-20-11-13(19)10-18-7-2-1-3-8-18/h4-6,9,13,19H,1-3,7-8,10-11H2/b17-14-
SMILES:C1CCN(CC1)CC(CO/N=C(/c1cccnc1)\Cl)O
Synonyms:
  • Bimoclomol [INN]
  • (+-)-N-(2-Hydroxy-3-piperidinopropoxy)nicotinimidoyl chloride
  • Unii-9Iyf14814M
  • N-[2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carboximidoyl chloride
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