CAS 13054-03-0

gly-pro-gly-gly

Description:

The chemical substance known as "gly-pro-gly-gly" is a peptide composed of the amino acids glycine (Gly) and proline (Pro) in a specific sequence. Its systematic name reflects its structure, which consists of two glycine residues flanking a proline residue, followed by another two glycine residues. This sequence contributes to its unique properties, including its potential role in biological processes and its influence on protein folding and stability. The CAS number 13054-03-0 identifies this specific peptide in chemical databases, facilitating its study and application in various fields, including biochemistry and pharmacology. Gly-pro-gly-gly may exhibit characteristics typical of peptides, such as solubility in water and the ability to form hydrogen bonds, which can affect its interactions with other biomolecules. Additionally, its structural features may influence its biological activity, making it of interest in research related to peptide synthesis, drug design, and therapeutic applications. Overall, gly-pro-gly-gly serves as a model for understanding peptide behavior and interactions in biological systems.

Formula: C₁₁H₁₈N₄O₅

InChI: InChI=1/C11H18N4O5/c12-4-9(17)15-3-1-2-7(15)11(20)14-5-8(16)13-6-10(18)19/h7H,1-6,12H2,(H,13,16)(H,14,20)(H,18,19)

SMILES: C1CC(C(=NCC(=NCC(=O)O)O)O)N(C1)C(=O)CN

Synonyms:

• Glycyl-prolyl-glycyl-glycine
• 3-de((4R)-4-Hydroxy-L-proline)-5-de-L-alanineantiarrhythmic peptide (cattle atrium)
• T-Gpgg
• Antiarrhythmic peptide (cattle atrium), 3-de((4R)-4-hydroxy-L-proline)-5-de-L-alanine-
• glycyl-L-prolylglycylglycine

H-Gly-Pro-Gly-Gly-OH

CAS: 13054-03-0

H-Gly-Pro-Gly-Gly-OH is a peptide that has been shown to have anti-inflammatory properties. It is an amide with four amino acids, Glycine, Proline, Glycine and Hydroxyproline. The terminal residues of this peptide are Glycine and Hydroxyproline. The optical properties of this peptide include the absorption maximum at 264 nm and the extinction coefficient at 25°C is approximately 5200 M−1 cm−1. This amide also has been clinically studied for its effects in humans with inflammatory disease such as arthritis. Kinetic studies have shown that this peptide binds to protein data through site specific interactions and molecular electrostatic potential simulations have shown that the chelate ring on the tetrapeptide interacts with the protein data.

Formula: C₁₁H₁₈N₄O₅

Purity: Min. 95%

Molecular weight: 286.28 g/mol

Ref: 3D-FG109051