CAS 13060-14-5

(+)-Yangambin

Description:

(+)-Yangambin is a naturally occurring chemical compound classified as a lignan, primarily derived from the bark of the Yangamba tree (Pseudolmedia laevis). It is known for its unique structural features, which include a complex arrangement of carbon rings and functional groups that contribute to its biological activity. This compound exhibits various pharmacological properties, including potential anti-inflammatory and neuroprotective effects. Additionally, (+)-Yangambin has garnered interest in the field of medicinal chemistry for its possible applications in treating certain health conditions. Its stereochemistry, indicated by the (+) designation, suggests that it is optically active, which can influence its interaction with biological systems. The compound's solubility, stability, and reactivity can vary depending on environmental conditions, making it a subject of interest for further research in both natural product chemistry and drug development. Overall, (+)-Yangambin represents a fascinating example of how natural compounds can possess significant therapeutic potential.

Formula: C₂₄H₃₀O₈

InChI: InChI=1S/C24H30O8/c1-25-17-7-13(8-18(26-2)23(17)29-5)21-15-11-32-22(16(15)12-31-21)14-9-19(27-3)24(30-6)20(10-14)28-4/h7-10,15-16,21-22H,11-12H2,1-6H3/t15-,16-,21+,22+/m0/s1

InChI key: InChIKey=HRLFUIXSXUASEX-RZTYQLBFSA-N

SMILES: O(C)C=1C=C([C@@H]2[C@@]3([C@@]([C@H](OC3)C4=CC(OC)=C(OC)C(OC)=C4)(CO2)[H])[H])C=C(OC)C1OC

Synonyms:

• (+)-O,O-Dimethyllirioresinol B
• (+)-Yangabin
• (+)-Yangambin
• (1S,3aR,4S,6aR)-Tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan
• 1H,3H-Furo[3,4-c]furan, 3aα,4,6,6aα-tetrahydro-1α,4α-bis(3,4,5-trimethoxyphenyl)-
• 1H,3H-Furo[3,4-c]furan, tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-, [1S-(1α,3aα,4α,6aα)]-
• 1H,3H-furo[3,4-c]furan, tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-, (1S,3aR,4S,6aR)-
• Lirioresinol B dimethyl ether
• Lirioresinol B, O,O-dimethyl-
• Lirioresinol B, dimethyl-

C10894

CAS: 13060-14-5

Formula: C₂₄H₃₀O₈

Purity: 97%

Molecular weight: 446.4902

Ref: IN-DA009JQZ

Yangambin

CAS: 13060-14-5

Yangambin

Purity: ≥98%

Molecular weight: 446.49g/mol

Ref: 54-BUP00896

Yangambin

CAS: 13060-14-5

Formula: C₂₄H₃₀O₈

Molecular weight: 446.50

Ref: 7W-GY0139

Yangambin

CAS: 13060-14-5

Formula: C₂₄H₃₀O₈

Purity: 95%~99%

Molecular weight: 446.496

Ref: BP-BP3405

Yangambin

CAS: 13060-14-5

Yangambin: selective PAF antagonist, hypotensive, inhibits Ca2+ influx, induces peripheral vasodilation, affects CNS.

Formula: C₂₄H₃₀O₈

Purity: 98.02%

Color and Shape: Solid

Molecular weight: 446.49

Ref: TM-TN2322

Yangambin

CAS: 13060-14-5

Yangambin is an acetate extract of the plant yangambin. Yangambin has been shown to have anti-cancer effects in vitro and in vivo, including a reduction in cell proliferation, differentiation and migration. It also has anti-inflammatory properties. This extract was studied on mice with squamous carcinoma and found to inhibit tumor growth. Yangambin is also known for its ability to stimulate the immune system by activating toll-like receptors (TLRs) that are involved in the recognition of pathogens. Yangambin activates TLR2, TLR4, and TLR9 pathways and induces a pro-inflammatory response against Leishmania parasites.

Formula: C₂₄H₃₀O₈

Purity: Min. 95%

Molecular weight: 446.5 g/mol

Ref: 3D-NAA06014