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CAS 130606-60-9

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N-DESMETHYLDILTIAZEM, HYDROCHLORIDE

Description:
N-Demethyldiltiazem hydrochloride is a chemical compound that belongs to the class of calcium channel blockers, primarily used in the treatment of cardiovascular conditions such as hypertension and angina. It is a derivative of diltiazem, which is known for its ability to inhibit calcium ion influx across cell membranes, leading to vasodilation and reduced cardiac workload. The hydrochloride salt form enhances its solubility and stability, making it suitable for pharmaceutical formulations. This compound typically appears as a white to off-white crystalline powder and is soluble in water and alcohol. Its pharmacological profile includes effects on both the heart and vascular smooth muscle, contributing to its therapeutic efficacy. Safety and efficacy profiles are established through clinical studies, and it is essential to consider potential side effects, drug interactions, and contraindications when prescribing. As with many medications, proper dosing and monitoring are crucial to ensure patient safety and optimal therapeutic outcomes.
Formula:C21H25ClN2O4S
Synonyms:
  • N-DemethyldiltiazemN-Monodesmethyldiltiazem,HCl
  • N-Monodesmethyldiltiazem
  • (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one Monohydrochloride
  • N-Demethyldiltiazem
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