CAS 13063-04-2

Nitidine chloride

Description:

Nitidine chloride is a chemical compound that belongs to the class of isoquinoline alkaloids, which are known for their diverse biological activities. It is characterized by its molecular structure, which includes a nitrogen-containing heterocyclic ring. This compound typically appears as a crystalline solid and is soluble in polar solvents. Nitidine chloride has garnered interest in pharmacology due to its potential therapeutic properties, including anti-cancer and anti-inflammatory effects. Its mechanism of action is thought to involve the modulation of various cellular pathways, although specific details may vary based on the context of its use. Additionally, like many alkaloids, it may exhibit a range of effects on biological systems, making it a subject of research in medicinal chemistry. Safety and handling precautions are essential when working with this compound, as it may pose health risks if not managed properly. Overall, Nitidine chloride represents a significant area of study within the field of natural products and drug development.

Formula: C₂₁H₁₈NO₄

InChI: InChI=1/C21H19NO4/c1-22-10-13-7-17(23-2)18(24-3)8-15(13)14-5-4-12-6-19-20(26-11-25-19)9-16(12)21(14)22/h4-10,18H,11H2,1-3H3

InChI key: InChIKey=QLDAACVSUMUMOR-UHFFFAOYSA-M

SMILES: C[N+]=1C=2C(C=3C(C1)=CC(OC)=C(OC)C3)=CC=C4C2C=C5C(=C4)OCO5.[Cl-]

Synonyms:

• 2,3-Dimethoxy-12-Methyl-3,12-Dihydro[1,3]Benzodioxolo[5,6-C]Phenanthridine
• 2,3-Dimethoxy-12-Methyl[1,3]Benzodioxolo[5,6-C]Phenanthridin-12-Ium
• 2,3-Dimethoxy-12-Methyl[1,3]Benzodioxolo[5,6-C]Phenanthridin-12-Ium Chloride
• 2,3-Dimethoxy-12-methyl-(1,3)-benzodioxolo(5,6-c)phenanthridinium chloride
• Dimethoxy-12-Methyl-,Chloride
• NSC 146397
• Nitidine
• Sml 0610
• [1,3]Benzodioxolo[5,6-c]phenanthridinium, 2,3-dimethoxy-12-methyl-, chloride
• [1,3]Benzodioxolo[5,6-c]phenanthridinium, 2,3-dimethoxy-12-methyl-, chloride (1:1)
• [1,3]Dioxolo[4,5]benzo[1,2-c]phenanthridinium, 2,3-
• Nitidine, chloride
• Nitidine chloride, 98%, from Zanthoxylum nitidum (Roxb.) DC.
• Angolinine
• 2,3-DiMethoxy-12-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-iuM chloride

[1,3]Benzodioxolo[5,6-c]phenanthridinium, 2,3-dimethoxy-12-methyl-, chloride (1:1)

CAS: 13063-04-2

Formula: C₂₁H₁₈ClNO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 383.8249

Ref: IN-DA000UQA

Nitidine chloride

CAS: 13063-04-2

Nitidine chloride

Purity: ≥95%

Molecular weight: 383.82g/mol

Ref: 54-BUP04692

Nitidine

CAS: 13063-04-2

Ref: 7W-GP2138

Nitidine Chloride

CAS: 13063-04-2

Nitidine chloride has protective effects on rats during myocardial ischemia/reperfusion, it also exerts an anti-inflammatory property by inhibiting TNF-α, IL-1β, and IL-6 production in association with reduced NF-κB and MAPK signaling pathways in RAW 264.7 cells. It has inhibitory effects on various tumors, such as renal cancer , breast cancer.

Formula: C₂₁H₁₈ClNO₄

Purity: 95%~99%

Molecular weight: 383.828

Ref: BP-BP0998

Nitidine Chloride

CAS: 13063-04-2

Formula: C₂₁H₁₈NO₄·Cl

Molecular weight: 348.38 35.45

Ref: 4Z-N-181001

Nitidine chloride

CAS: 13063-04-2

1.

Formula: C₂₁H₁₈ClNO₄

Purity: 96.59% - 98.91%

Color and Shape: Solid

Molecular weight: 383.82

Ref: TM-T5S0761

Nitidine chloride

CAS: 13063-04-2

Natural alkaloid

Formula: C₂₁H₁₈NO₄Cl

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 383.83

Ref: 5G-80506

Nitidine Chloride

Controlled Product

CAS: 13063-04-2

Formula: C₂₁H₁₈NO₄·Cl

Color and Shape: Neat

Molecular weight: 383.82

Ref: TR-N490110

Nitidine chloride

CAS: 13063-04-2

Nitidine chloride is a natural alkaloid, which is isolated from the roots of Zanthoxylum nitidum. This compound functions primarily as an inhibitor of topoisomerase I and II, disrupting the replication of DNA and resulting in antitumor effects. Nitidine chloride also exhibits multiple biological activities, including anti-inflammatory, antimicrobial, and antimalarial properties.

Formula: C₂₁H₁₈ClNO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 383.82 g/mol

Ref: 3D-FN65676

2,3-Dimethoxy-12-methyl-[1,3]dioxolo[4′,5′:4,5]benzo[1,2-c]phenanthridin-12-ium chloride

CAS: 13063-04-2

Formula: C₂₁H₁₈ClNO₄

Purity: 97%

Molecular weight: 383.83

Ref: 10-F223922