CAS 13067-94-2

2-Chloro-5-nitroquinoline

Description:

2-Chloro-5-nitroquinoline is a heterocyclic organic compound characterized by a quinoline backbone, which consists of a fused benzene and pyridine ring. The presence of a chlorine atom at the second position and a nitro group at the fifth position of the quinoline structure significantly influences its chemical properties and reactivity. This compound typically appears as a yellow to orange crystalline solid and is sparingly soluble in water but more soluble in organic solvents. It exhibits a range of biological activities, making it of interest in medicinal chemistry and pharmaceutical research. The nitro group can participate in reduction reactions, while the chlorine atom can serve as a site for further substitution reactions. Additionally, 2-Chloro-5-nitroquinoline may exhibit fluorescence properties, which can be useful in various analytical applications. As with many nitro-containing compounds, it is essential to handle this substance with care due to potential toxicity and environmental concerns. Proper safety measures should be taken when working with this compound in laboratory settings.

Formula: C₉H₅ClN₂O₂

InChI: InChI=1S/C9H5ClN2O2/c10-9-5-4-6-7(11-9)2-1-3-8(6)12(13)14/h1-5H

InChI key: InChIKey=IICVTJMDHNPPOP-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1C2=C(N=C(Cl)C=C2)C=CC1

Synonyms:

• NSC 261562
• 2-Chloro-5-nitroquinoline
• Quinoline, 2-chloro-5-nitro-
• 5-Nitro-2-chloroquinoline

Quinoline, 2-chloro-5-nitro-

CAS: 13067-94-2

Formula: C₉H₅ClN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 208.6012

Ref: IN-DA000US6

2-Chloro-5-nitroquinoline

CAS: 13067-94-2

2-Chloro-5-nitroquinoline

Purity: 90%

Molecular weight: 208.60g/mol

Ref: 54-OR74613

2-Chloro-5-nitroquinoline

CAS: 13067-94-2

Formula: C₉H₅ClN₂O₂

Purity: 98%

Molecular weight: 208.6

Ref: 10-F221041

2-Chloro-5-nitroquinoline

Controlled Product

CAS: 13067-94-2

Applications 2-Chloro-5-nitroquinoline is used in the synthesis of potent, orally active corticotropin-releasing factor-1 receptor antagonists.
References Takeda, K., et al.: BIoorg. Med. Chem., 20, 6559 (2012); Verheij, M.H.P., et al.: J. Med. Chem., 55, 8603 (2012); Takeda, K., et al.: Bioorg. Med. Chem. Lett., 22, 5372 (2012);

Formula: C₉H₅ClN₂O₂

Color and Shape: Neat

Molecular weight: 208.6

Ref: TR-C374695

2-Chloro-5-nitroquinoline

CAS: 13067-94-2

2-Chloro-5-nitroquinoline is an oxidized aminoquinoline that is synthesized from nitric acid and benzene. It contains a nitro group, which makes it susceptible to oxidation. 2-Chloro-5-nitroquinoline is used as a solvent for rubber, plastics, and waxes. It can also be used as a solvent in the production of quinolines and other nitrogen compounds. Nitration of this compound produces 2-chloroquinoline, which can be transformed into 2-chloroquinolinium hydroxide by reaction with sodium hydroxide. The substituent on the ortho position can be determined by oleum or bromine water.

Formula: C₉H₅ClN₂O₂

Purity: Min. 95%

Molecular weight: 208.6 g/mol

Ref: 3D-NAA06794