CAS 130676-58-3
:Inosine, 2′,3′-dideoxy-, 5′-acetate
Description:
Inosine, 2′,3′-dideoxy-, 5′-acetate, with the CAS number 130676-58-3, is a modified nucleoside derivative of inosine. This compound features a dideoxy modification at the 2′ and 3′ positions of the ribose sugar, which means it lacks hydroxyl groups at these positions, making it resistant to hydrolysis and altering its biological activity. The presence of an acetate group at the 5′ position further modifies its properties, potentially influencing its solubility and interaction with biological systems. Inosine derivatives are often studied for their roles in nucleic acid metabolism and their potential therapeutic applications, particularly in antiviral and anticancer research. The structural modifications can affect its ability to act as a substrate for various enzymes, impacting its function in cellular processes. Overall, this compound is of interest in biochemical and pharmaceutical research due to its unique structural characteristics and potential biological implications.
Formula:C12H14N4O4
InChI:InChI=1S/C12H14N4O4/c1-7(17)19-4-8-2-3-9(20-8)16-6-15-10-11(16)13-5-14-12(10)18/h5-6,8-9H,2-4H2,1H3,(H,13,14,18)/t8-,9+/m0/s1
InChI key:InChIKey=MVUMVNRFAFXMSZ-DTWKUNHWSA-N
SMILES:O=C1C2=C(N(C=N2)[C@@H]3O[C@H](COC(C)=O)CC3)NC=N1
Synonyms:- 5'-Acetyl-2',3'-dideoxyinosine
- Inosine, 2′,3′-dideoxy-, 5′-acetate
- Sjy-Ii-15-95
- [(2S,5R)-5-(6-oxo-3,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl]methyl acetate
- ddI-5'-Ac
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Found 2 products.
5'-O-Acetyl-2',3'-dideoxyinosine
CAS:<p>5'-O-Acetyl-2',3'-dideoxyinosine is a nucleoside analogue that inhibits viral replication. It is a potent activator of the immune system and has been shown to be effective against cancer cells. 5'-O-Acetyl-2',3'-dideoxyinosine was originally synthesized as an antiviral agent, but it was found to be ineffective in this function. The drug binds to the ribonucleotide reductase enzyme, which converts ribonucleotides into deoxyribonucleotides and is essential for the production of DNA. The drug blocks the conversion of ribonucleotides into deoxyribonucleotides, preventing DNA synthesis and replication. This drug has also been shown to have anticancer activity by inhibiting DNA synthesis and cell division.</p>Formula:C12H14N4O4Purity:Min. 95%Molecular weight:278.26 g/mol
