CAS 1306760-85-9

Ozanimod

Description:

Ozanimod is a selective sphingosine 1-phosphate receptor modulator, primarily used in the treatment of autoimmune diseases such as multiple sclerosis and ulcerative colitis. Its mechanism of action involves the modulation of lymphocyte trafficking, effectively reducing the number of circulating lymphocytes and thereby mitigating inflammatory responses. Chemically, ozanimod is characterized by its unique structure, which includes a bicyclic core and various functional groups that contribute to its receptor selectivity and pharmacological profile. It exhibits good oral bioavailability and a favorable pharmacokinetic profile, allowing for once-daily dosing. Ozanimod has been shown to have a relatively low incidence of side effects, although it may cause bradycardia and liver enzyme elevations in some patients. As a novel therapeutic agent, ozanimod represents a significant advancement in the management of chronic inflammatory conditions, offering a targeted approach to treatment that minimizes systemic immunosuppression. Its development underscores the importance of receptor-targeted therapies in modern pharmacology.

Formula: C₂₃H₂₅ClN₄O₃

Synonyms:

• Benzonitrile, 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)aMino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-Methylethoxy)- (HCl salt)
• 5-[3-[(1R)-1-(2-hydroxyethylamino)-2,3-dihydro-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile:hydrochloride
• R-Ozanimod Hydrochloride
• Ozanimod HCl salt
• Ozanimod.hcl
• 5-[3-[(1R)-1-(2-hydroxyethylamino)-2,3-dihydro-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile

(R)-Ozanimod HCl

CAS: 1306760-85-9

Formula: C₂₃H₂₄N₄O₃·HCl

Color and Shape: Off-White Solid

Molecular weight: 404.47 36.46

Ref: 4Z-O-077004