CAS 130717-51-0

[4,5-bis(4-methoxyphenyl)-1,3-thiazol-2-yl](4-methylpiperazin-1-yl)methanone hydrochloride (1:1)

Description:

The chemical substance "[4,5-bis(4-methoxyphenyl)-1,3-thiazol-2-yl](4-methylpiperazin-1-yl)methanone hydrochloride (1:1)" with CAS number 130717-51-0 is a synthetic compound characterized by its complex structure, which includes a thiazole ring and piperazine moiety. This compound typically exhibits properties such as solubility in polar solvents due to the presence of functional groups, including methoxy and piperazine, which enhance its interaction with biological systems. It may demonstrate biological activity, potentially acting as a pharmacological agent, although specific activity would depend on its interaction with biological targets. The hydrochloride salt form indicates that it is likely to be more stable and soluble in aqueous environments, which is advantageous for pharmaceutical applications. Additionally, the presence of multiple aromatic rings suggests potential for π-π stacking interactions, which could influence its binding properties in biological contexts. Overall, this compound's unique structural features contribute to its potential utility in medicinal chemistry and drug development.

Formula: C₂₃H₂₆ClN₃O₃S

InChI: InChI=1/C23H25N3O3S.ClH/c1-25-12-14-26(15-13-25)23(27)22-24-20(16-4-8-18(28-2)9-5-16)21(30-22)17-6-10-19(29-3)11-7-17;/h4-11H,12-15H2,1-3H3;1H

SMILES: CN1CCN(CC1)C(=O)c1nc(c2ccc(cc2)OC)c(c2ccc(cc2)OC)s1.Cl

Synonyms:

• Methanone, [4,5-bis(4-methoxyphenyl)-2-thiazolyl](4-methyl-1-piperazinyl)-, hydrochloride (1:1)
• Piperazine, 1-((4,5-bis(4-methoxyphenyl)-2-thiazolyl)carbonyl)-4-methyl-, monohydrochloride
• [4,5-Bis(4-methoxyphenyl)-1,3-thiazol-2-yl](4-methylpiperazin-1-yl)methanone hydrochloride (1:1)

FR122047 (hydrochloride)

CAS: 130717-51-0

Formula: C₂₃H₂₆ClN₃O₃S

Purity: 99%

Color and Shape: Solid

Molecular weight: 459.9888

Ref: IN-DA000UUW

FR 122047

CAS: 130717-51-0

FR 122047

Purity: ≥98%

Molecular weight: 459.99g/mol

Ref: 54-BUP03875

FR 122047

CAS: 130717-51-0

FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nM

Formula: C₂₃H₂₆ClN₃O₃S

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 459.99

Ref: TM-T22790