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CAS 1307262-15-2

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  • AKV-9
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    AKV-9

    CAS:
    <p>AKV-9 is an inhibitor of mutant Cu/Zn superoxide dismutase (SOD1), effectively preventing SOD1-induced protein aggregation and providing protection against SOD1-induced cytotoxicity in PC-12 cells, with an EC50 of 0.3 μM. Additionally, AKV-9 has been shown to improve amyotrophic lateral sclerosis (ALS) in mouse models and extend their lifespan.</p>
    Formula:C16H14F6O3
    Color and Shape:Solid
    Molecular weight:368.27

    Ref: TM-T203125