CAS 13073-22-8
:D-Buthionine
Description:
D-Buthionine, also known as D-buthionine sulfoximine (DBSO), is a synthetic compound primarily recognized for its role as an inhibitor of the enzyme gamma-glutamylcysteine synthetase, which is crucial in the biosynthesis of glutathione. This compound is characterized by its ability to deplete cellular glutathione levels, making it a valuable tool in research related to oxidative stress and cancer biology. D-Buthionine is often utilized in studies investigating the effects of reduced antioxidant capacity on cellular processes and in the context of enhancing the efficacy of certain chemotherapeutic agents. The substance is typically available as a white to off-white powder and is soluble in water and various organic solvents. Its application extends to both in vitro and in vivo studies, although caution is advised due to its potential cytotoxic effects at high concentrations. As with any chemical, proper handling and safety protocols should be followed to mitigate any risks associated with its use.
Formula:C8H17NO2S
InChI:InChI=1S/C8H17NO2S/c1-2-3-5-12-6-4-7(9)8(10)11/h7H,2-6,9H2,1H3,(H,10,11)/t7-/m1/s1
InChI key:InChIKey=LAXXPOJCFVMVAX-SSDOTTSWSA-N
SMILES:C([C@H](C(O)=O)N)CSCCCC
Synonyms:- (R)-2-Amino-4-(butylthio)butanoic acid
- <span class="text-smallcaps">D</span>-Homocysteine, S-butyl-
- Butyric acid, 2-amino-4-(butylthio)-, <span class="text-smallcaps">D</span>-
- D-2-Amino-4-(butylthio)butyric Acid
- S-Butyl-<span class="text-smallcaps">D</span>-homocysteine
- S-Butyl-D-homocysteine
- n-Butyl-<span class="text-smallcaps">D</span>-homocysteine
- n-Butyl-D-homocysteine
- D-Homocysteine, S-butyl-
- Butyric acid, 2-amino-4-(butylthio)-, D-
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