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CAS 13073-96-6

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Decloxizine hydrochloride

Description:
Decloxizine hydrochloride is a chemical compound primarily recognized for its use as an antihistamine and antiallergic agent. It belongs to the class of medications known as phenothiazines, which are characterized by their ability to block histamine receptors, thereby alleviating allergic symptoms. The substance is typically presented as a hydrochloride salt, enhancing its solubility in water, which is crucial for its bioavailability when administered. Decloxizine exhibits a range of pharmacological effects, including sedation and antiemetic properties, making it useful in treating conditions such as motion sickness and anxiety. Its mechanism of action involves antagonism of H1 histamine receptors, which helps reduce the physiological responses associated with allergic reactions. Additionally, like many antihistamines, it may cause side effects such as drowsiness, dry mouth, and dizziness. Safety and efficacy profiles are established through clinical studies, and it is essential to adhere to prescribed dosages to minimize adverse effects. As with any medication, it is important to consult healthcare professionals for appropriate use and potential interactions with other drugs.
Formula:C21H30Cl2N2O2
InChI:InChI=1/C21H28N2O2.2ClH/c24-16-18-25-17-15-22-11-13-23(14-12-22)21(19-7-3-1-4-8-19)20-9-5-2-6-10-20;;/h1-10,21,24H,11-18H2;2*1H
SMILES:c1ccc(cc1)C(c1ccccc1)N1CCN(CC1)CCOCCO.Cl.Cl
Synonyms:
  • Decloxizine Hcl
  • Hydroxydiethylphenamine
  • 2-(2-(4-(Diphenylmethyl)-1-piperazinyl)ethoxy)ethanol dihydrochloride
  • Ethanol, 2-(2-(4-(diphenylmethyl)-1-piperazinyl)ethoxy)-, dihydrochloride
  • 2-{2-[4-(Diphenylmethyl)Piperazin-1-Yl]Ethoxy}Ethanol Dihydrochloride
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