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CAS 13074-31-2

:

1,2,3,4-Tetrahydro papaverine

Description:
1,2,3,4-Tetrahydro papaverine is a semi-synthetic derivative of papaverine, which is an alkaloid originally derived from the opium poppy. This compound is characterized by its tetrahydro structure, indicating the presence of a saturated ring system that contributes to its pharmacological properties. It typically appears as a white to off-white crystalline solid and is soluble in organic solvents, such as ethanol and chloroform, but has limited solubility in water. The compound exhibits various biological activities, including vasodilatory effects, which can influence blood flow and have potential therapeutic applications. Its mechanism of action is primarily associated with the inhibition of phosphodiesterase enzymes, leading to increased levels of cyclic AMP. Due to its structural modifications compared to papaverine, 1,2,3,4-Tetrahydro papaverine may exhibit altered potency and selectivity for specific biological targets. As with many alkaloids, safety and toxicity profiles are essential considerations in its use, necessitating further research to fully understand its pharmacokinetics and therapeutic potential.
Formula:C20H25NO4
InChI:InChI=1/C20H25NO4.ClH/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16;/h5-6,10-12,16,21H,7-9H2,1-4H3;1H
InChI key:InChIKey=YXWQTVWJNHKSCC-UHFFFAOYSA-N
SMILES:C(C1C=2C(=CC(OC)=C(OC)C2)CCN1)C3=CC(OC)=C(OC)C=C3
Synonyms:
  • (+/-)-Tetrahydropapaverine
  • (±)-N-Norlaudanosine
  • (±)-Norlaudanosine
  • 1,2,3,4-Tetrahydropapaverine
  • 1-(3,4-Dimethoxybenzyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline
  • 1-(3,4-Dimethoxybenzyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinolinium Chloride
  • 1-[(3,4-Dimethoxyphenyl)Methyl]-1,2,3,4-Tetrahydro-6,7-Dimethoxyisoquinoline
  • Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratryl-
  • Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-
  • NOR-LAUDANOSINE
  • See more synonyms
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