CAS 130800-90-7

Sipatrigine

Description:

Sipatrigine, with the CAS number 130800-90-7, is a chemical compound that belongs to the class of substances known as sodium channel blockers. It is primarily studied for its potential therapeutic applications, particularly in the treatment of neurological disorders such as epilepsy. The compound exhibits a mechanism of action that involves the modulation of sodium ion flow across neuronal membranes, which can help stabilize neuronal excitability and reduce seizure activity. Sipatrigine is characterized by its specific molecular structure, which contributes to its pharmacological properties. In terms of solubility, it typically shows moderate solubility in organic solvents, while its solubility in water may vary. Safety and toxicity profiles are essential considerations in its development, and ongoing research aims to elucidate its efficacy and side effects in clinical settings. As with many pharmaceutical compounds, understanding its pharmacokinetics, including absorption, distribution, metabolism, and excretion, is crucial for its potential use in medical applications.

Formula: C₁₅H₁₆Cl₃N₅

InChI: InChI=1S/C15H16Cl3N5/c1-22-2-4-23(5-3-22)15-20-8-11(14(19)21-15)10-6-9(16)7-12(17)13(10)18/h6-8H,2-5H2,1H3,(H2,19,20,21)

InChI key: InChIKey=PDOCBJADCWMDGL-UHFFFAOYSA-N

SMILES: ClC1=C(C=C(Cl)C=C1Cl)C=2C(N)=NC(=NC2)N3CCN(C)CC3

Synonyms:

• 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine
• 2-(4-Methyl-piperazin-1-yl)-5-(2,3,5-trichloro-phenyl)-pyrimidin-4-ylamine
• 2-(4-Methylpiperazin-1-Yl)-5-(2,3,5-Trichlorophenyl)-Pyrimidin-4-Amine
• 4-Pyrimidinamine, 2-(4-methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-
• 619C89
• Bw 619C89
• L-Glutamic Acid, N-[4-[2-(2-Amino-4,7-Dihydro-4-8 Oxo-1H-Pyrrolo[2,3-D] Pyrimidin-5-Yl)Ethyl]Benzoyl]-, Disodium Salt, Heptahydrate
• disodium (2S)-2-[({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]phenyl}carbonyl)amino]pentanedioate
• Sipatrigine

4-Pyrimidinamine, 2-(4-methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-

CAS: 130800-90-7

Formula: C₁₅H₁₆Cl₃N₅

Purity: 95%

Molecular weight: 372.6800

Ref: IN-DA000UYO

Sipatrigine

CAS: 130800-90-7

Sipatrigine

Purity: ≥98%

Molecular weight: 372.68g/mol

Ref: 54-BUP05028

Sipatrigine

CAS: 130800-90-7

Formula: C₁₅H₁₆Cl₃N₅

Molecular weight: 372.68

Ref: 4Z-S-242001

Sipatrigine

CAS: 130800-90-7

Sipatrigine (619C89) is an inhibitor of glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channels.

Formula: C₁₅H₁₆Cl₃N₅

Purity: 98.64% - 99.77%

Color and Shape: Solid

Molecular weight: 372.68

Ref: TM-T16887