CAS 13081-18-0

Ethyl 3,3,3-trifluoro-2-oxopropanoate

Description:

Ethyl 3,3,3-trifluoro-2-oxopropanoate, with the CAS number 13081-18-0, is an organic compound characterized by its trifluoromethyl group and ester functional group. This compound features a propanoate backbone, where the ethyl group is attached to the ester, and a ketone functionality is present at the second carbon. The presence of three fluorine atoms significantly influences its chemical properties, enhancing its reactivity and polarity compared to non-fluorinated analogs. Ethyl 3,3,3-trifluoro-2-oxopropanoate is typically a colorless liquid at room temperature and is soluble in organic solvents. It is often utilized in synthetic organic chemistry, particularly in the development of pharmaceuticals and agrochemicals, due to its ability to participate in various chemical reactions, including nucleophilic substitutions and condensation reactions. The trifluoromethyl group imparts unique electronic properties, making it a valuable building block in the synthesis of more complex fluorinated compounds. Safety precautions should be taken when handling this substance, as it may pose health risks if inhaled or ingested.

Formula: C₅H₅F₃O₃

InChI: InChI=1S/C5H5F3O3/c1-2-11-4(10)3(9)5(6,7)8/h2H2,1H3

InChI key: InChIKey=KJHQVUNUOIEYSV-UHFFFAOYSA-N

SMILES: C(C(C(F)(F)F)=O)(OCC)=O

Synonyms:

• 3,3,3-Trifluoro-2-Oxopropanoic Acid Ethyl Ester
• 3,3,3-Trifluoropyruvic acid ethyl ester
• E-Tfpa
• Ethyl 2-Oxo-3,3,3-Trifluoro Propionate
• Ethyl 2-oxo-3,3,3-trifluoropropanoate
• Ethyl 3,3,3-Trifluoro-2-Oxopropanoate
• Ethyl 3,3,3-Trifluoropyruvate
• Ethyl trifluoropyruvate 98%
• Ethyltrifluoropyruvate98%
• Methyl 3,3,3-Trifluoro-2-Oxopropanoate
• Propanoic acid, 3,3,3-trifluoro-2-oxo-, ethyl ester
• Pyruvic acid, trifluoro-, ethyl ester
• Rarechem Al Bi 1300
• Trifluoropyruvic Acid Ethyl Ester

Ethyl Trifluoropyruvate

CAS: 13081-18-0

Formula: C₅H₅F₃O₃

Purity: >98.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 170.09

Ref: 3B-T1434

Ethyl trifluoropyruvate, 97%

CAS: 13081-18-0

Ethyl trifluoropyruvate acts as a building block in synthetic chemistry for the synthesis of fluorine containing compounds. It is also used as a reagent for the preparation of potential biologically active compounds like highly enantioselective organocatalytic hydroxyalkylation of indoles. This Ther

Formula: C₅H₅F₃O₃

Purity: 97%

Color and Shape: Liquid, Clear colorless to pale yellow

Molecular weight: 170.09

Ref: 02-B20611

Ethyl 3,3,3-trifluoro-2-oxopropanoate

CAS: 13081-18-0

Formula: C₅H₅F₃O₃

Purity: 95%

Color and Shape: Liquid

Molecular weight: 170.0866

Ref: IN-DA0034X0

Ethyl trifluoropyruvate

CAS: 13081-18-0

Ethyl trifluoropyruvate

Formula: C₅H₅F₃O₃

Purity: 98%

Color and Shape: clear. colourless liquid

Molecular weight: 170.09g/mol

Ref: 54-PC3288G

Ethyl trifluoropyruvate

CAS: 13081-18-0

Formula: C₅H₅F₃O₃

Purity: 97.0%

Color and Shape: Liquid

Molecular weight: 170.087

Ref: 10-F003224

Trifluoropyruvic Acid Ethyl Ester

Controlled Product

CAS: 13081-18-0

Stability Moisture Sensitive
Applications Trifluoropyruvic Acid Ethyl Ester is used as a reagent in the preparation of potential biologically active compounds such as in the highly enantioselective organocatalytic hydroxyalkylation of indoles.
References Toeroek, B. et al.: Angew. Chem. Int. Ed., 44, 3086 (2005); Wolf, C. et al.: Adv. Synth. Cat., 353, 760 (2011);

Formula: C₅H₅F₃O₃

Color and Shape: Neat

Molecular weight: 170.09

Ref: TR-T792700

Trifluoropyruvic acid ethyl ester

CAS: 13081-18-0

Trifluoropyruvic acid ethyl ester is a synthetic compound and an enantiopure ligand for coordination chemistry. It is activated by the addition of hydroxyl groups to the molecule, which can be achieved with hydrochloric acid. Trifluoropyruvic acid ethyl ester has been shown to form stable complexes with metal ions, such as copper and zinc. This complex has been shown to bind to receptors in biological systems, including non-steroidal anti-inflammatory agents. Trifluoropyruvic acid ethyl ester binds to receptors on cell membranes by intermolecular hydrogen bonding between the phenolic hydroxyl group and the receptor's aromatic ring system, which induces conformational changes in the receptor protein that leads to its activation or inhibition.

Formula: C₅H₅F₃O₃

Purity: Min. 98%

Color and Shape: Colorless Powder

Molecular weight: 170.09 g/mol

Ref: 3D-FT55208