CAS 130848-06-5

Decursinol angelate

Description:

Decursinol angelate is a chemical compound classified as a natural product, specifically a type of coumarin derivative. It is primarily derived from plants in the Apiaceae family, particularly from the roots of Angelica gigas. This compound is characterized by its unique structure, which includes a decursinol moiety and an angelate ester group. Decursinol angelate exhibits various biological activities, including anti-inflammatory, antioxidant, and potential anticancer properties, making it of interest in pharmacological research. Its solubility is generally moderate in organic solvents, and it may have limited solubility in water. The compound's stability can be influenced by environmental factors such as light and temperature. As with many natural products, its extraction and purification can be complex, often requiring specific methods to isolate it from plant matrices. Overall, decursinol angelate represents a fascinating area of study within natural product chemistry, with potential applications in medicine and health.

Formula: C₁₉H₂₀O₅

InChI: InChI=1S/C19H20O5/c1-5-11(2)18(21)23-16-9-13-8-12-6-7-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/b11-5-/t16-/m0/s1

InChI key: InChIKey=AGABNGOXUSXQDD-XKGFZTIGSA-N

SMILES: CC1(C)OC=2C(C[C@@H]1OC(/C(=C\C)/C)=O)=CC3=C(C2)OC(=O)C=C3

Synonyms:

• 2-Butenoic acid, 2-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b′]dipyran-7-yl ester, (2Z)-
• 2-Butenoic acid, 2-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b′]dipyran-7-yl ester, [S-(Z)]-
• 2-Butenoicacid, 2-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-ylester, [S-(Z)]-
• 2H,6H-Benzo[1,2-b:5,4-b']dipyran, 2-butenoic acid deriv.
• Acutilobin
• Decursinol angelate

Decursinol angelate

CAS: 130848-06-5

Formula: C₁₉H₂₀O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 328.3591

Ref: IN-DA009B3Z

(S)-8,8-Dimethyl-2-Oxo-7,8-Dihydro-2H,6H-Pyrano[3,2-G]Chromen-7-Yl (Z)-2-Methylbut-2-Enoate

CAS: 130848-06-5

(S)-8,8-Dimethyl-2-Oxo-7,8-Dihydro-2H,6H-Pyrano[3,2-G]Chromen-7-Yl (Z)-2-Methylbut-2-Enoate

Purity: 98%

Molecular weight: 328.36g/mol

Ref: 54-OR1023111

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate

Purity: ≥98%

Molecular weight: 328.36g/mol

Ref: 54-BUP10926

Decursinol angelate

CAS: 130848-06-5

Formula: C₁₉H₂₀O₅

Molecular weight: 328.36

Ref: 7W-GY9577

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.Decursinol angelate has protective effects against amyloid β-protein-induced oxidative stress in the PC12 cell line. It improves wound healing by upregulating the expression of genes encoding extracellular matrix remodeling proteins, inflammatory cytokines, and growth factors. Decursinol angelate has in vitro and in vivo antifungal activity against Magnaporthe oryzae, the causal agent of rice blast.

Formula: C₁₉H₂₀O₅

Purity: 95%~99%

Molecular weight: 328.364

Ref: BP-BP1812

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.

Formula: C₁₉H₂₀O₅

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 328.36

Ref: TM-TN1557

Decursinol angelate

CAS: 130848-06-5

Lactone

Formula: C₁₉H₂₀O₅

Purity: ≥ 90.0 % (HPLC)

Molecular weight: 328.36

Ref: 5G-84209

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate is a bioactive compound, which is derived from the roots of plants such as Angelica gigas, a species commonly used in traditional Asian medicine. This compound is a coumarin derivative, known for its potential pharmacological properties. Decursinol angelate’s mode of action involves the modulation of inflammatory pathways, particularly through the inhibition of key enzymes and cytokines involved in inflammatory responses, such as COX-2 and TNF-alpha. This modulation leads to a reduction in the synthesis of pro-inflammatory mediators, which can be beneficial in managing inflammation-related conditions.

Formula: C₁₉H₂₀O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 328.36 g/mol

Ref: 3D-FFA84806

Decursinol angelate - Bio-X ™

CAS: 130848-06-5

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₉H₂₀O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 328.36 g/mol

Ref: 3D-BD300081