CAS 130860-11-6

1-[(2R,3S,4S,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-phenoxycarbothioyloxy-5-(trityloxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione

Description:

The chemical substance known as 1-[(2R,3S,4S,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-phenoxycarbothioyloxy-5-(trityloxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione, with the CAS number 130860-11-6, is a complex organic compound characterized by its multi-functional groups and stereochemistry. It features a pyrimidine core, which is a six-membered ring containing nitrogen atoms, and is substituted with various groups that enhance its chemical reactivity and solubility. The presence of a tetrahydrofuran moiety contributes to its cyclic structure, while the tert-butyl(dimethyl)silyl and trityloxymethyl groups provide steric hindrance and potential for further chemical modifications. This compound may exhibit properties such as solubility in organic solvents, stability under certain conditions, and potential biological activity, making it of interest in medicinal chemistry and drug development. Its intricate structure suggests that it could participate in various chemical reactions, including nucleophilic substitutions and coupling reactions, which are valuable in synthetic organic chemistry.

Formula: C₄₁H₄₄N₂O₇SSi

InChI: InChI=1/C41H44N2O7SSi/c1-40(2,3)52(4,5)50-36-35(49-39(51)47-32-24-16-9-17-25-32)33(48-37(36)43-27-26-34(44)42-38(43)45)28-46-41(29-18-10-6-11-19-29,30-20-12-7-13-21-30)31-22-14-8-15-23-31/h6-27,33,35-37H,28H2,1-5H3,(H,42,44,45)/t33-,35+,36+,37-/m1/s1

Uridine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5'-O-(triphenylmethyl)-, 3'-(O-phenyl carbonothioate) (9CI)

CAS: 130860-11-6

Formula: C₄₁H₄₄N₂O₇SSi

Color and Shape: Solid

Molecular weight: 736.9478

Ref: IN-DA000V0S

2’-O-(tert-Butyldimethylsilyl)-3’-O-(phenoxythioncarbonyl)-5’-O-trityluridine

CAS: 130860-11-6

Ref: 7W-GN6930

2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine

CAS: 130860-11-6

2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine (TBS-PTU) is a modified nucleoside that has antiviral activity. TBS-PTU inhibits viral replication by interfering with the synthesis of viral RNA and DNA. The antiviral activity of TBS-PTU is increased in the presence of ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides. TBS-PTU is used as a building block for DNA synthesis and as a precursor to other modified nucleosides.

Formula: C₄₁H₄₄N₂O₇SSi

Purity: Min. 95%

Molecular weight: 736.95 g/mol

Ref: 3D-NB16514