CAS 130878-68-1
:Fmoc-Val-OSu
Description:
Fmoc-Val-OSu, or Fluorenylmethyloxycarbonyl-Valine N-hydroxysuccinimide ester, is a chemical compound commonly used in peptide synthesis and bioconjugation. It features a fluorenylmethyloxycarbonyl (Fmoc) protecting group attached to the amino acid valine, which allows for selective protection of the amino group during peptide assembly. The N-hydroxysuccinimide (OSu) moiety facilitates the formation of stable amide bonds with nucleophiles, such as amines, making it a valuable reagent in the synthesis of peptide derivatives and conjugates. Fmoc-Val-OSu is typically a white to off-white solid and is soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Its stability under standard laboratory conditions makes it suitable for various applications in organic synthesis and medicinal chemistry. The compound is sensitive to moisture and should be stored in a dry environment to maintain its reactivity. Overall, Fmoc-Val-OSu is an essential tool in the field of peptide chemistry, enabling the efficient synthesis of complex biomolecules.
Formula:C24H24N2O6
InChI:InChI=1/C24H24N2O6/c1-14(2)22(23(29)32-26-20(27)11-12-21(26)28)25-24(30)31-13-19-17-9-5-3-7-15(17)16-8-4-6-10-18(16)19/h3-10,14,19,22H,11-13H2,1-2H3,(H,25,30)/t22-/m0/s1
InChI key:JPJMNCROLRPFHI-QFIPXVFZSA-N
SMILES:CC(C)[C@@H](C(=O)ON1C(=O)CCC1=O)N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:- 2,5-dioxopyrrolidin-1-yl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valinate
- N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Valine 2,5-Dioxo-1-Pyrrolidinyl Ester
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N-Fmoc-L-valine N-succinimidyl ester, 95%
CAS:N-Fmoc-L-valine N-succinimidyl ester is useful for solid phase peptide synthesis techniques. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar productFormula:C24H24N2O6Purity:95%Molecular weight:436.46Fmoc-Val-Osu
CAS:Fmoc-Val-OsuFormula:C24H24N2O6Purity:95%Color and Shape:Solid-PowderMolecular weight:436.45715Fmoc-Val-Osu
CAS:Fmoc-Val-OsuFormula:C24H24N2O6Purity:94%Color and Shape:Solid-PowderMolecular weight:436.45715Fmoc-L-Val-OSu
CAS:Formula:C24H24N2O6Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:436.46Fmoc-L-valine N-hydroxysuccinimide ester
CAS:Fmoc-L-valine N-hydroxysuccinimide ester is a pegylated, cytotoxic drug that is used in the treatment of cancer. It is delivered to cells by an organic solvent, which causes uptake into the cell and intracellular delivery. Fmoc-L-valine N-hydroxysuccinimide ester forms particles that are excreted from the body through the kidneys. This drug has been shown to be effective against a number of different types of cancer cells, including breast cancer, lung cancer, and colon cancer cells. Fmoc-L-valine N-hydroxysuccinimide ester has been shown to be cytotoxic in vivo and in vitro against tumor tissue and MFC-7 cells with no effect on normal tissue or healthy cells. Fmoc-L-valine N-hydroxysuccinimide ester can also be used as aFormula:C24H24N2O6Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:436.46 g/molFmoc-Val-OSu
CAS:Bachem ID: 4003501.
Formula:C24H24N2O6Purity:99.0%Color and Shape:WhiteMolecular weight:436.46
