CAS 13090-91-0
:16-O-deacetylfusidic acid
Description:
16-O-deacetylfusidic acid is a naturally occurring steroid antibiotic derived from the fungus *Fusidium coccineum*. It is characterized by its unique structure, which includes a fused ring system typical of steroid compounds, contributing to its biological activity. This compound exhibits antibacterial properties, particularly against Gram-positive bacteria, making it valuable in clinical applications. Its mechanism of action primarily involves inhibiting bacterial protein synthesis by interfering with the elongation factor G, which is crucial for the translocation step during translation. 16-O-deacetylfusidic acid is often used in topical formulations due to its effectiveness against skin infections. Additionally, it has a relatively low toxicity profile, which enhances its suitability for therapeutic use. The compound is typically administered in the form of ointments or creams, and its solubility characteristics allow for effective absorption through the skin. Overall, 16-O-deacetylfusidic acid is an important compound in the field of medicinal chemistry, particularly in the development of antibiotics for treating bacterial infections.
Formula:C29H46O5
InChI:InChI=1/C28H44O5/c1-15(2)7-6-8-17(26(32)33)24-20-13-22(30)25-19(28(20,5)14-23(24)31)10-9-18-16(3)21(29)11-12-27(18,25)4/h7,16,18-23,25,29-31H,6,8-14H2,1-5H3,(H,32,33)/b24-17-/t16-,18?,19-,20-,21+,22+,23-,25-,27-,28+/m0/s1
Synonyms:- 16-O-16-Epideacetylfusidic acid
- 16-O-Desacetylfusidic acid
- 29-Nordammara-17(20),24-dien-21-oic acid, 3,11,16-trihydroxy-, (3alpha,4alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-
- (2Z)-6-methyl-2-[(3alpha,4alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-3,11,16-trihydroxy-4,10,14-trimethylgonan-17-ylidene]hept-5-enoic acid
- 16-O-Deacetylfusidic acid
- Fusidic Acid Impurity O
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