CAS 13093-88-4

Perimetazine

Description:

Perimetazine is an antihistamine belonging to the phenothiazine class, primarily used for its sedative and antiemetic properties. It functions by blocking histamine H1 receptors, which helps alleviate allergic reactions and symptoms such as nausea and vomiting. The substance is characterized by its ability to cross the blood-brain barrier, leading to central nervous system effects, including sedation. Perimetazine is typically administered in tablet form and may be used in various formulations, including those for motion sickness and as a premedication for surgical procedures. Its pharmacological profile includes anticholinergic effects, which can lead to side effects such as dry mouth, dizziness, and drowsiness. Due to its sedative properties, caution is advised when operating machinery or driving after consumption. As with many medications, potential interactions with other drugs and contraindications in certain medical conditions should be considered. Overall, perimetazine is a useful therapeutic agent in managing specific allergic and nausea-related conditions, but it requires careful monitoring for side effects and interactions.

Formula: C₂₂H₂₈N₂O₂S

InChI: InChI=1S/C22H28N2O2S/c1-16(14-23-11-9-17(25)10-12-23)15-24-19-5-3-4-6-21(19)27-22-8-7-18(26-2)13-20(22)24/h3-8,13,16-17,25H,9-12,14-15H2,1-2H3

InChI key: InChIKey=WYRWAVVTDKZRIJ-UHFFFAOYSA-N

SMILES: C(C(CN1CCC(O)CC1)C)N2C=3C(SC=4C2=CC=CC4)=CC=C(OC)C3

Synonyms:

• 1-(3-(2-Methoxyphenothiazin-10-yl)-2-methylpropyl)-4-piperidinol
• 1-[3-(2-Methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]-4-piperidinol
• 1-[3-(2-Methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]piperidin-4-ol
• 13093-88-4
• 2-Methoxy-10-[2-methyl-3-(4-hydroxypiperidino)propyl]phenothiazine
• 3-Methoxy-10-[3-(4-hydroxypiperidyl)-2-methylpropyl]phenothiazine
• 4-Piperidinol, 1-[3-(2-methoxyphenothiazin-10-yl)-2-methylpropyl]-
• 4-piperidinol, 1-[3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]-
• An 1317
• Leptryl
• Perimethazine
• Rp 9159
• Perimetazine

Perimethazine-d4

Controlled Product

CAS: 13093-88-4

Applications Perimethazine-d4, is the labeled analogue of Perimethazine (P287000), a novel Antipsychotic drug. It has shown to cause sedation, hypothermia, muscle relaxation, and other signs of central depression in rabbits.
References keda, Sh., Nippon Yakurigaku Zasshi, 72 (1), 113 (1976);

Formula: C₂₂D₄H₂₄N₂O₂S

Color and Shape: Neat

Molecular weight: 388.56

Ref: TR-P287002

Perimethazine

Controlled Product

CAS: 13093-88-4

Formula: C₂₂H₂₈N₂O₂S

Color and Shape: Neat

Molecular weight: 384.535

Ref: TR-P287000

Perimetazine

CAS: 13093-88-4

Perimetazine has effects on central nervous system depressent such as sedative and muscle relaxant effects.

Formula: C₂₂H₂₈N₂O₂S

Color and Shape: Solid

Molecular weight: 384.53

Ref: TM-T33936