CAS 13095-61-9

26-Hydroxycholesterol

Description:

26-Hydroxycholesterol is a naturally occurring oxysterol, which is a derivative of cholesterol. It is characterized by the presence of a hydroxyl group at the 26th carbon position of the cholesterol molecule. This compound plays a significant role in various biological processes, including cholesterol metabolism and regulation of lipid homeostasis. It is known to influence gene expression and has been implicated in the modulation of immune responses and inflammation. 26-Hydroxycholesterol can also act as a signaling molecule, affecting cellular pathways related to cholesterol synthesis and uptake. In terms of physical properties, it is typically a white to off-white solid, soluble in organic solvents, and exhibits limited solubility in water. Its biological significance has garnered interest in research related to cardiovascular diseases, neurodegenerative disorders, and metabolic syndromes. As a member of the oxysterol family, it can also serve as a precursor for the synthesis of other bioactive compounds.

Formula: C₂₇H₄₆O₂

InChI: InChI=1S/C27H46O2/c1-18(17-28)6-5-7-19(2)23-10-11-24-22-9-8-20-16-21(29)12-14-26(20,3)25(22)13-15-27(23,24)4/h8,18-19,21-25,28-29H,5-7,9-17H2,1-4H3/t18?,19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChI key: InChIKey=FYHRJWMENCALJY-CCDZVGGQSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(CO)C)C)[H])[H]

Synonyms:

• (3Beta)-Cholest-5-Ene-3,26-Diol
• (3β)-Cholest-5-ene-3,26-diol
• 26-Hydroxycholesterol
• Cholest-5-Ene-3,26-Diol
• Cholest-5-ene-3,26-diol, (3beta)-
• Cholest-5-ene-3,26-diol, (3β)-
• Cholest-5-ene-3beta,26-diol
• Cholest-5-ene-3β,26-diol
• Nsc 226105
• Cholest-5-ene-3-beta,26-diol

(25RS)-26-Hydroxycholesterol-24,24,26,26-d4

Controlled Product

CAS: 13095-61-9

Formula: C₂₇D₄H₄₂O₂

Color and Shape: Neat

Molecular weight: 406.69

Ref: TR-H918051