CAS 130952-46-4
:Ozagrel sodium
Description:
Ozagrel sodium is a synthetic compound primarily used as a thromboxane A2 receptor antagonist, which plays a significant role in inhibiting platelet aggregation and promoting vasodilation. It is classified as a non-steroidal anti-inflammatory drug (NSAID) and is often utilized in the management of conditions related to cardiovascular health, particularly in the treatment of acute ischemic stroke and other thromboembolic disorders. The substance is characterized by its ability to selectively inhibit the action of thromboxane A2, thereby reducing the risk of clot formation. Ozagrel sodium is typically administered intravenously and is known for its rapid onset of action. In terms of its chemical properties, it is a sodium salt, which enhances its solubility in aqueous solutions, making it suitable for parenteral administration. Safety and efficacy profiles are well-documented, although potential side effects may include bleeding complications and gastrointestinal disturbances, common to many antiplatelet agents. Overall, Ozagrel sodium represents a valuable therapeutic option in the realm of cardiovascular medicine.
Formula:C13H12N2NaO2
InChI:InChI=1/C13H12N2O2.Na/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15;/h1-8,10H,9H2,(H,16,17);/q;+1/b6-5+;
SMILES:c1cc(ccc1C=CC(=O)O)Cn1ccnc1.[Na]
Synonyms:- (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid sodium salt
- sodium (2E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]prop-2-enoate
- 2-propenoic acid, 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-, sodium salt, (2E)- (1:1)
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Found 2 products.
(E/Z)-Ozagrel sodium
CAS:(E/Z)-Ozagrel (sodium) [(E/Z)-OKY-046 (sodium)] is a mixture of the EZ isomers of Ozagrel (sodium). It acts as a thromboxane A2 (TXA2) synthase inhibitor. As an antiplatelet agent, Ozagrel (sodium) selectively inhibits human platelet aggregation, with an IC50 of 53.12 μM.Formula:C13H11N2NaO2Color and Shape:SolidMolecular weight:250.228
