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CAS 1309768-22-6

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2-hydroxy-4-(trifluoromethoxy)phenylboronic acid

Description:
2-Hydroxy-4-(trifluoromethoxy)phenylboronic acid is an organoboron compound characterized by the presence of a boronic acid functional group, which is known for its ability to form reversible covalent bonds with diols, making it useful in various applications, including organic synthesis and medicinal chemistry. The compound features a phenyl ring substituted with a hydroxy group and a trifluoromethoxy group, which enhances its reactivity and solubility in polar solvents. The trifluoromethoxy group contributes to the compound's unique electronic properties, potentially influencing its interactions in biological systems. This compound is typically used in the development of pharmaceuticals and as a reagent in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is vital for constructing complex organic molecules. Additionally, the presence of the boronic acid moiety allows for the formation of stable complexes with sugars, making it relevant in the field of glycoscience. Overall, 2-hydroxy-4-(trifluoromethoxy)phenylboronic acid is a versatile compound with significant implications in both synthetic and medicinal chemistry.
Formula:C7H6BF3O4
Synonyms:
  • Boronic acid, B-[2-hydroxy-4-(trifluoromethoxy)phenyl]-
  • 2-hydroxy-4-(trifluoromethoxy)phenylboronic acid
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