CAS 1309784-09-5

ITK inhibitor 2

CAS: 1309784-09-5

Formula: C₂₅H₃₃N₅O₂

Purity: 99.66%

Molecular weight: 435.5618

Ref: IN-DA01V4L4

ITK inhibitor 2

CAS: 1309784-09-5

ITK inhibitor 2

Purity: ≥98%

Molecular weight: 435.56g/mol

Ref: 54-BUP20943

(αS)-N,α-Dimethyl-N-[2-(4,5,6,7-tetrahydro-6,6-dimethyl-1H-indazol-3-yl)-1H-indol-6-yl]-4-morpholineacetamide

CAS: 1309784-09-5

(αS)-N,α-Dimethyl-N-[2-(4,5,6,7-tetrahydro-6,6-dimethyl-1H-indazol-3-yl)-1H-indol-6-yl]-4-morpholineacetamide (PDE10A) is a potential drug target for various inflammatory diseases such as reactive arthritis and autoimmune diseases. It is a hydrophilic molecule that functions by binding to the enzyme cyclic guanosine monophosphate (cGMP) phosphodiesterase 10A (PDE10A). PDE10A hydrolyzes cGMP to GMP. This inhibitor blocks the production of cAMP and therefore reduces inflammation and pain. PDE10A also has anti-proliferative effects on certain cancer cells in vitro.

Formula: C₂₅H₃₃N₅O₂

Purity: Min. 95%

Molecular weight: 435.6 g/mol

Ref: 3D-JCC78409

ITK inhibitor 2

CAS: 1309784-09-5

ITK inhibitor 2 (compound 4) is a potent and selective ITK inhibitor with an IC50= 2 nM.

Formula: C₂₅H₃₃N₅O₂

Purity: 99.67%

Color and Shape: Solid

Molecular weight: 435.56

Ref: TM-T11690