CAS 1309935-89-4

N-Acetyl Mesalamine-d3

CAS: 1309935-89-4

Formula: C₉H₆D₃NO₄

Color and Shape: Pale Brown Solid

Molecular weight: 198.19

Ref: 4Z-M-172

N-Acetyl Mesalazine-d3

Controlled Product

CAS: 1309935-89-4

Applications N-Acetyl Mesalazine-d3 is the labeled analogue of N-Acetyl Mesalazine (A168320), a metabolite of Mesalazine. A Salicylic Acid derivative. Inhibitor of recombinant human thiopurine methyltransferase (hTPMT).
References Bondesen, S., et al.: Br. J. Clin. Pharmacol., 25, 269 (1988); Brogden, R., et al.: Drugs, 38, 500 (1989); Jensen, J., et al.: Biochem. Pharmacol., 45, 1201 (1993); Liu, Z., et al.: Drug Metab. Dispos., 23, 246 (1995); Vree, T., et al.: Clin. Drug Invest., 20, 35 (2000)

Formula: C₉₂H₃H₆NO₄

Color and Shape: Neat

Molecular weight: 198.19

Ref: TR-A168323

N-Acetyl mesalazine-d3

CAS: 1309935-89-4

N-Acetyl mesalazine is a drug that is used to treat ulcerative colitis, Crohn's disease and other inflammatory bowel diseases. It is an acetylated form of the active component of mesalazine, which works by blocking the production of inflammatory substances in the gut. The 3D structure of N-acetyl mesalazine has been determined using nuclear magnetic resonance (NMR) techniques, which showed that it binds to a receptor on the surface of cells called TGR5. This receptor activates ion channels and regulates cell growth.

Formula: C₉H₆D₃NO₄

Purity: Min. 95%

Molecular weight: 198.19 g/mol

Ref: 3D-JCC93589