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CAS 130996-24-6

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Dehydro Lacidipine

Description:
Dehydro Lacidipine is a chemical compound primarily recognized for its role as a calcium channel blocker, which is utilized in the treatment of hypertension and certain cardiovascular conditions. It is a derivative of lacidipine, featuring a modified structure that enhances its pharmacological properties. The compound exhibits a high affinity for L-type calcium channels, leading to vasodilation and a subsequent reduction in blood pressure. Dehydro Lacidipine is characterized by its lipophilicity, which allows for effective tissue penetration and prolonged action. Its molecular structure includes a dihydropyridine ring, which is essential for its activity. The compound is typically administered in oral form and is known for its relatively favorable side effect profile compared to other antihypertensive agents. Additionally, it undergoes hepatic metabolism, and its pharmacokinetics can be influenced by factors such as age and liver function. Overall, Dehydro Lacidipine represents a significant therapeutic option in managing cardiovascular health.
Formula:C26H31NO6
InChI:InChI=1/C26H31NO6/c1-8-31-24(29)21-16(3)27-17(4)22(25(30)32-9-2)23(21)19-13-11-10-12-18(19)14-15-20(28)33-26(5,6)7/h10-15H,8-9H2,1-7H3/b15-14+
Synonyms:
  • (E)-4-[2-[3-(1,1-Dimethylethoxy)-3-oxo-1-prphenyl]-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Diethyl Ester
  • GR 510922qopenyl]
  • Gr 51092X
  • diethyl 4-{2-[(1E)-3-tert-butoxy-3-oxoprop-1-en-1-yl]phenyl}-2,6-dimethylpyridine-3,5-dicarboxylate
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