CAS 131-03-3

Rauwolscine

Description:

Rauwolscine, also known as alpha-yohimbine, is an indole alkaloid derived from the bark of the Rauwolfia species, particularly Rauwolfia serpentina. It is structurally related to yohimbine and exhibits similar pharmacological properties. Rauwolscine is characterized by its ability to act as an antagonist of alpha-2 adrenergic receptors, which can lead to increased sympathetic nervous system activity. This property makes it of interest in various applications, including potential use in weight loss and as an aphrodisiac. The compound is typically found in a crystalline form and is soluble in organic solvents but has limited solubility in water. Rauwolscine has been studied for its effects on blood pressure and its potential role in enhancing athletic performance, although its safety and efficacy in these contexts require further investigation. As with many alkaloids, it may have side effects, including increased heart rate and anxiety, particularly at higher doses. Proper handling and dosage are essential due to its potent biological activity.

Formula: C₂₁H₂₆N₂O₃

InChI: InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1

InChI key: InChIKey=BLGXFZZNTVWLAY-DIRVCLHFSA-N

SMILES: C(OC)(=O)[C@H]1[C@]2(C[C@]3(C4=C(C=5C(N4)=CC=CC5)CCN3C[C@]2(CC[C@@H]1O)[H])[H])[H]

Synonyms:

• (-)-Rauwolscine
• (16Beta,17Alpha,20Alpha)-17-Hydroxy-16-(Methoxycarbonyl)Yohimban-4-Ium
• 20α-Yohimban-16β-carboxylic acid, 17α-hydroxy-, methyl ester
• Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.
• Corynanthidine
• Isoyohimbine
• Mesoyohimbine
• Methyl (16Beta,17Alpha,20Alpha)-17-Hydroxyyohimban-16-Carboxylate
• Methyl (16Beta,17Alpha,20Alpha)-17-Hydroxyyohimban-16-Carboxylate Hydrochloride (1:1)
• Methyl (16Beta,20Alpha)-17-Hydroxyyohimban-16-Carboxylate
• Methyl (17Alpha,20Alpha)-17-Hydroxyyohimban-16-Carboxylate Hydrochloride
• Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16β,17α,20α)-
• meso-Yohimbine
• α-Yohimbine

Rauwolscine

CAS: 131-03-3

Formula: C₂₁H₂₆N₂O₃

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 354.4427

Ref: IN-DA000VAP

α-Yohimbine

CAS: 131-03-3

Alpha-Yohimbine is a 5-HT1A receptor agonist, it is strong selective 2-adrenoceptor antagonist. Alpha-Yohimbine possess aphrodisiac effect.

Formula: C₂₁H₂₆N₂O₃

Purity: 98%

Color and Shape: White Solid

Molecular weight: 354.44

Ref: TM-TN3393

α-Yohimbine

CAS: 131-03-3

Formula: C₂₁H₂₆N₂O₃

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 354.45

Ref: BP-SBP00676

alpha-Yohimbine

CAS: 131-03-3

Alpha-Yohimbine is a naturally occurring alkaloid that acts primarily as an alpha-2 adrenergic receptor antagonist. It is derived from the bark of the Yohimbe tree (Pausinystalia johimbe) found in Central Africa, as well as from other plants like Rauwolfa. Its mode of action involves blocking alpha-2 adrenergic receptors, which leads to increased levels of norepinephrine and enhanced sympathetic nervous system activity.

Formula: C₂₁H₂₆N₂O₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 354.44 g/mol

Ref: 3D-FY145483

Yohimbine EP Impurity B

CAS: 131-03-3

Formula: C₂₁H₂₆N₂O₃

Molecular weight: 354.45

Ref: ST-EA-CP-Y1003